Protein Info for PFR28_00551 in Pseudomonas sp. RS175
Annotation: Arginine deiminase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 84% identical to ARCA_PSEAE: Arginine deiminase (arcA) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG orthology group: K01478, arginine deiminase [EC: 3.5.3.6] (inferred from 97% identity to pba:PSEBR_a1198)Predicted SEED Role
"Arginine deiminase (EC 3.5.3.6)" in subsystem Arginine Deiminase Pathway or Arginine and Ornithine Degradation (EC 3.5.3.6)
MetaCyc Pathways
- L-arginine degradation XIII (reductive Stickland reaction) (5/5 steps found)
- L-arginine degradation V (arginine deiminase pathway) (4/4 steps found)
- L-arginine degradation XIV (oxidative Stickland reaction) (2/6 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.5.3.6
Use Curated BLAST to search for 3.5.3.6
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (418 amino acids)
>PFR28_00551 Arginine deiminase (Pseudomonas sp. RS175) MTTEKVKYGVHSEAGKLRKVMVCSPGLAHQRLTPNNCDELLFDDVIWVNQAKRDHFDFVT KMRERGIDVLEMHNLLTDIVAMPDALDWILQRKITANSVGLGLVNEVGSWLRSLEPRKIA EFLIGGVSADDLPDSFGGKTIQMFRDFLGHSSFILPPLPNTQFTRDTTCWIYGGVTLNPM YWPARRQETLLTTAIYKFHPEFTHADFQIWYGDPDQDHGNATLEGGDVMPIGNGVVLIGM GERSSRQAIGQLALNLFKHKAVERVIVAGLPKSRAAMHLDTVFSFCDRDLVTIFPEVVGQ IVAFSLRPDESKPGGIDVRREEGSFLDTVAAALKLPALRVVETGGNSFAAEREQWDDGNN VVAMEPGVVIGYDRNTYTNTLLRKAGVEVITISASELGRGRGGGHCMTCPIIRDPIDY