Protein Info for PFR28_00510 in Pseudomonas sp. RS175

Annotation: Acyl-homoserine lactone acylase QuiP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 816 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF01804: Penicil_amidase" amino acids 52 to 802 (751 residues), 630.1 bits, see alignment E=3.9e-193

Best Hits

Swiss-Prot: 83% identical to QUIP_PSEPF: Acyl-homoserine lactone acylase QuiP (quiP) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: K01434, penicillin amidase [EC: 3.5.1.11] (inferred from 87% identity to pba:PSEBR_a1158)

Predicted SEED Role

"Penicillin acylase (EC 3.5.1.11)" (EC 3.5.1.11)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.11

Use Curated BLAST to search for 3.5.1.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (816 amino acids)

>PFR28_00510 Acyl-homoserine lactone acylase QuiP (Pseudomonas sp. RS175)
MASPASTSFFPRLGVAATVAGVLGLSGCQAWNTQDTVPPTSGVQPLKGLAQNVTVRRNAM
GMPLIESSSFHDALFALGYVHAGDRITQMVTLRLLAQGRLAEMSGAERLDVDRYMRAVNL
KKSADELYKASSPRLKRFFEVYARGVNAYLFRYRDKLPADLAATGYKPEYWKPEDSALMF
CLLNFSQSANLPEEIASLVLAQTVNNDKLAWLSPSYPDEPLPLSEADKLQGIRLNGQIPG
LAELDKASNQLAGLNLPGAGSSNDWVIAPQRSRGGKSLLASASQGPLSAPSSWSPVQIRA
PKYQAAGVSVPGIPMILAGFNGKVAWSMTSVQGDNQDLFLEKIRRQGNSLSYEVNGKWQP
VTVRNETYFVKGQRPIREAVFETRHGPLLNSAQGLAMANGLGLALQTPAFTDDRTLDAFF
DLSRAQNAEKASDATREIRAMAMNVIFADASNIGWQVTGRYPNRREGEGLLPSPGWDGRY
DWEGYADPMAHPYDQDPAQGWLGNANQRVIPHGYGMQLSNSWAAPERGERLAELAGAGKH
DVRSLTAMQYDQTTPFAAKLKKVFEAPGLAQPLKQAIEALPPADRAKAREAYTRLMAFDG
RLSPVSADAAIYELFLQESMKQIFLDELGPENSQAWKALVANGQLSYSAQADHLLGREDS
PFWDDVRTPQKEDKAVILARALAAAISVGDSQLGTDHKAWQWGKLHRYEWKNGSGQTVRG
PLSAGGDATTLNTSAFAWGQDFNTVLAPTLRLIVDFSQPEPLLVQGGVGQSGNPASPSYL
SGIDPWIKAQYQNVPLQPQNFDRAYGKTRLTLAPGR