Protein Info for PFR28_00392 in Pseudomonas sp. RS175

Annotation: Sodium, potassium, lithium and rubidium/H(+) antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 44 to 65 (22 residues), see Phobius details amino acids 83 to 105 (23 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 154 to 174 (21 residues), see Phobius details amino acids 180 to 200 (21 residues), see Phobius details amino acids 214 to 231 (18 residues), see Phobius details amino acids 237 to 256 (20 residues), see Phobius details amino acids 268 to 287 (20 residues), see Phobius details amino acids 307 to 333 (27 residues), see Phobius details amino acids 357 to 380 (24 residues), see Phobius details amino acids 393 to 416 (24 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 7 to 417 (411 residues), 228.3 bits, see alignment E=7.3e-72 TIGR00831: Na+/H+ antiporter" amino acids 9 to 544 (536 residues), 436 bits, see alignment E=9.6e-135

Best Hits

KEGG orthology group: K03316, monovalent cation:H+ antiporter, CPA1 family (inferred from 95% identity to pba:PSEBR_a1059)

Predicted SEED Role

"Na+/H+ antiporter" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (548 amino acids)

>PFR28_00392 Sodium, potassium, lithium and rubidium/H(+) antiporter (Pseudomonas sp. RS175)
MQSAYTVLILLTLVGVSRLIGRLIPLPLPLVQIGAGAVLAWPSLGLHVTLDPELFLFLFL
PPLLFSDGWRMPKRELWRLRGPILTLAVGLVLFTVVGAGYFIHWLLPDIPLPMAFALAAV
LSPTDAVAVSAIARDRLPGPLMHMLQGEALMNDASGLVTFKFALAAAVTGVFSLANASVT
FVLVAVGGLLVGVALSWLMGRLRAWMVARGWDDPATHVVFMLLLPFAAYVVAERLGASGI
LSAVAAGMMQSWLDLLPRQTGTRLLNRSVWALLEFAFNGLIFLLLGLQLPDIIKAVTSHE
TTLWPTLFYRCLDVVVIFLVLLVLRFVWVQSIWRLSGLLRRWRGKGELTLVPTARSCWLL
TFGGVRGAVTLAGVLSVPLLLGAGEPFPERDLLIFIAAGVILLSLIAACIALPLLLKGIE
KSPDDKRRNEVRDAWRKTAEAAIRALEVEEPSEATSTPDAAQAALATEVKARLMSEYRHQ
LDVFNDSAEAQALAFEMDLLERRLRLKAYRAQRLELYRLSRHHQIGDDVLREVLGELDLA
EANLGLGK