Protein Info for PFR28_00266 in Pseudomonas sp. RS175

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 361 TIGR00229: PAS domain S-box protein" amino acids 69 to 181 (113 residues), 55.3 bits, see alignment E=7.1e-19 PF08448: PAS_4" amino acids 71 to 179 (109 residues), 39 bits, see alignment E=2.5e-13 PF00989: PAS" amino acids 75 to 175 (101 residues), 33.5 bits, see alignment E=1.1e-11 PF13426: PAS_9" amino acids 75 to 177 (103 residues), 49.8 bits, see alignment E=1.1e-16 PF08447: PAS_3" amino acids 87 to 170 (84 residues), 33.9 bits, see alignment E=9.5e-12 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 185 to 347 (163 residues), 145 bits, see alignment E=1.7e-46 PF00990: GGDEF" amino acids 189 to 346 (158 residues), 156.4 bits, see alignment E=1.7e-49

Best Hits

KEGG orthology group: None (inferred from 88% identity to pba:PSEBR_a902)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (361 amino acids)

>PFR28_00266 hypothetical protein (Pseudomonas sp. RS175)
MNLRTFVRRYCLDFRLVTNALIRLHKALSALVSSLAQQGFDSQRWPATRDEEAPDRRIGS
ICPELAATVFSHGREGVALVDPYGRVIDVNEAFTRLTGYGQDEVRGRELNAHRMVRRLAA
FYAPMKNALDFHGHWSGEIQSSHKDGREMTSRISISAVHDRHGNVQHYVALLSDMTQVKQ
RLQLLERDARYDALTQLPNRLLLAERMRQALGKARIHQHQVAIAFIDLDGFKALNDSYGH
DWGDRVLQIVAARINATLREGDTLARLGGDEFVAGLVGLQEVEDSEPLLKRMLAAANAPI
LIGAQTVEIAASIGVAFFPEHGQEVDALISKADQAMYLSKKAGGNRLAFCPTRFISVNSE
A