Protein Info for PFR28_00179 in Pseudomonas sp. RS175
Annotation: Intermembrane phospholipid transport system ATP-binding protein MlaF
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 59% identical to MLAF_ECOLI: Intermembrane phospholipid transport system ATP-binding protein MlaF (mlaF) from Escherichia coli (strain K12)
KEGG orthology group: K02065, putative ABC transport system ATP-binding protein (inferred from 96% identity to pba:PSEBR_a852)Predicted SEED Role
"Uncharacterized ABC transporter, ATP-binding protein YrbF"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (269 amino acids)
>PFR28_00179 Intermembrane phospholipid transport system ATP-binding protein MlaF (Pseudomonas sp. RS175) MSADNAYAVELKGLSFKRGTRSIFNDIDIRIPRGKVTGIMGPSGCGKTTLLRLMGAQLRP SAGEVWVNGQNIPKLSRSDLFDARKHMGVLFQSGALFTDLDVFENVAFPLRVHTDLPEEM IRDIVLLKLQAVGLRGAIDLMPDELSGGMKRRVALARAIALDPKILMYDEPFVGQDPIAM GVLVRLIRLLNDALGITSIVVSHDLAETASIADYIYVIGDGQVLGQGTPQELKASDNPRI RQFMKGDADGPVAFHFPATDYRTDLLGKR