Protein Info for PFLU_RS27720 in Pseudomonas fluorescens SBW25

Annotation: PepSY domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 147 to 171 (25 residues), see Phobius details amino acids 192 to 223 (32 residues), see Phobius details amino acids 338 to 359 (22 residues), see Phobius details PF03929: PepSY_TM" amino acids 12 to 361 (350 residues), 215.1 bits, see alignment E=9.7e-68

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU5630)

Predicted SEED Role

"putative iron-regulated membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K378 at UniProt or InterPro

Protein Sequence (367 amino acids)

>PFLU_RS27720 PepSY domain-containing protein (Pseudomonas fluorescens SBW25)
MKSKTIRRWSFIHTWTSLICTVFLLLLALTGLPLVFHHEIDHLLGNEPELAQMPADTPQL
NLEQLVAKAQAHRPGEAMQYLAWDEDDKNGVIAIMAATAGTEPNSSHTFMLDARTGDALE
TPAANGGFTLFLLRLHVDMFAGLPGKWLLAFMGVLFVVAIISGTVLYLPFMRRLKFATVR
RDKSTRLRWLDLHNLIGVVTLTWALVVGVTGVISACADLIIAAWRQDSLSAMIEPYKNAP
PLTQRAPATELLNIAAKAAPGMEPDFIAFPGTRFSSEHHYAVFMKGSTHLTSHLLTPVLI
DASTLAVTAIAERPWYMDAMGMSQPLHFGDYGGMPMKVLWAVLDVLTIVVLGSGVYLWVV
RRKAGKP