Protein Info for PFLU_RS26810 in Pseudomonas fluorescens SBW25

Annotation: GAF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 PF01590: GAF" amino acids 35 to 160 (126 residues), 42.2 bits, see alignment E=1.2e-14 PF02518: HATPase_c" amino acids 314 to 427 (114 residues), 70.6 bits, see alignment E=1.6e-23

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU5455)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K2Q4 at UniProt or InterPro

Protein Sequence (439 amino acids)

>PFLU_RS26810 GAF domain-containing protein (Pseudomonas fluorescens SBW25)
MQMPHLPAPLPANEQERLRSLEHLGILDSAPEPGFDDIVLLATNLCDVPIALVSLVDKER
QWFKACIGLDVRETHRDLAFCAHAILSPDEVLVVEDAALDARFEHSALVLGPPYIRFYAG
APIRDDRGFALGTVCVIDTRARTLTVAQHNALLALARQTASLLQLRLLSEQRELRARHLE
HELAQAQALGRQAEQFMHHAKRVSSLGMVAASIAHDFNNLLQALSASLQMVRLRARRPDD
VERFSDAGLQAVDQGRLLVNHLLTSVRHDSPNLMCIDVNERLESMRDVLLRTASDGVELS
LDLAAAGTGVLCEEAQLSAAVINLLANARDALGGNGRVHIRSRLVSVEQDEALAAGNYLL
LSIADNGPGMHEELAAQVFEPFFTTKCAGKGTGLGLSQVLEFAQRAGGTVKVQTAPGAGT
TMNLYLRALGRIDTHLPVG