Protein Info for PFLU_RS25420 in Pseudomonas fluorescens SBW25

Annotation: 2-keto-3-deoxygluconate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 31 to 53 (23 residues), see Phobius details amino acids 64 to 83 (20 residues), see Phobius details amino acids 104 to 131 (28 residues), see Phobius details amino acids 140 to 161 (22 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 231 to 253 (23 residues), see Phobius details amino acids 265 to 288 (24 residues), see Phobius details amino acids 305 to 323 (19 residues), see Phobius details amino acids 336 to 357 (22 residues), see Phobius details amino acids 364 to 384 (21 residues), see Phobius details amino acids 390 to 412 (23 residues), see Phobius details amino acids 424 to 446 (23 residues), see Phobius details PF02447: GntP_permease" amino acids 10 to 447 (438 residues), 505.3 bits, see alignment E=1.4e-155 TIGR00791: transporter, gluconate:H+ symporter (GntP) family" amino acids 12 to 448 (437 residues), 464.8 bits, see alignment E=1.7e-143 PF03600: CitMHS" amino acids 25 to 395 (371 residues), 46.1 bits, see alignment E=3.8e-16

Best Hits

KEGG orthology group: K03299, gluconate:H+ symporter, GntP family (inferred from 100% identity to pfs:PFLU5180)

Predicted SEED Role

"Gluconate transporter family protein" in subsystem D-gluconate and ketogluconates metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K1Y7 at UniProt or InterPro

Protein Sequence (449 amino acids)

>PFLU_RS25420 2-keto-3-deoxygluconate permease (Pseudomonas fluorescens SBW25)
MAASPGFGLLAYAAIAIIALIVLIARYRLNPFIVITLVSIGLALMAGMPADTIMGSYEAG
VGKTLGHIALVVALGTMLGKMMAESGGAEQVARTLINRFGERNAHWAMVCIAFLVGLPLF
FEVGFVLLVPIAFTVARRVGVSILMVGLPMVAGLSVVHALVPPHPAAMMAVLAYNASVGQ
TVLYAILIGIPTAIIAGPLYAKFIVPRIHLPAENPLERQFIDREPRTRLPSFTLTMGTIL
LPVVLMMIGGWANVISTPGTGFNQFLLFIGNSVIALLVATLVSFWTLGIAQGFNRESILT
FTNECLAPTASITLLVGAGGGLNRILVDAGVTNEILGLAHAFHLSPLVMGWLFAALMRIA
TGSATVAMTTASGVVAPVAMGLGYPHPELLVLATGAGSVIFSHVNDGGFWLIKEYFNMTV
IQTFKTWTVLETLISVVAFGLTYGLSLVL