Protein Info for PFLU_RS23850 in Pseudomonas fluorescens SBW25

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 398 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 44 to 64 (21 residues), see Phobius details amino acids 80 to 101 (22 residues), see Phobius details amino acids 113 to 135 (23 residues), see Phobius details amino acids 147 to 168 (22 residues), see Phobius details amino acids 174 to 194 (21 residues), see Phobius details amino acids 215 to 241 (27 residues), see Phobius details amino acids 248 to 266 (19 residues), see Phobius details amino acids 278 to 296 (19 residues), see Phobius details amino acids 302 to 325 (24 residues), see Phobius details amino acids 337 to 358 (22 residues), see Phobius details amino acids 364 to 386 (23 residues), see Phobius details PF07690: MFS_1" amino acids 18 to 246 (229 residues), 49.7 bits, see alignment E=1.3e-17 amino acids 221 to 393 (173 residues), 58.1 bits, see alignment E=3.9e-20

Best Hits

Swiss-Prot: 74% identical to Y3302_PSEA7: Uncharacterized MFS-type transporter PSPA7_3302 (PSPA7_3302) from Pseudomonas aeruginosa (strain PA7)

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU4866)

Predicted SEED Role

"Xanthine transporter,putative" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3JZI5 at UniProt or InterPro

Protein Sequence (398 amino acids)

>PFLU_RS23850 MFS transporter (Pseudomonas fluorescens SBW25)
MPDTQRPLAVTLQVVSIVLFTFIGYLNIGIPLAVLPGYVHSELGYGAVIAGLVISVQYLA
TLLSRPYAGKIIDTLGSKRAVLIGLAGCGLSGVFMLLAAWFSSLPALSLGSLLIGRLVLG
SAESLVGSGAIGWGIGRVGAANTAKVISWNGIASYGALAVGAPLGVVLVRHFGLWSMGVS
IILLAIVGLLLAWNKVAAPLVAGVRLPFMNVLGRVLPHGCALALGSIGFGTIATFITLYY
TTQHWDNAVWALSLFGASFIGARLLFGNLINRIGGFRVAIACLSVEVLGLLLLWLAPDAH
LALAGAALSGFGFSLVFPALGVEAVNLVPASSRGSAVGAYSLFIDLSLGITGPLAGAVAA
GFGFASIFLFAALAALGGLLLSVYLYRQAPKAREARGD