Protein Info for PFLU_RS22305 in Pseudomonas fluorescens SBW25

Annotation: CPBP family intramembrane metalloprotease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 transmembrane" amino acids 12 to 39 (28 residues), see Phobius details amino acids 51 to 71 (21 residues), see Phobius details amino acids 101 to 116 (16 residues), see Phobius details amino acids 126 to 152 (27 residues), see Phobius details amino acids 158 to 177 (20 residues), see Phobius details amino acids 198 to 219 (22 residues), see Phobius details amino acids 232 to 258 (27 residues), see Phobius details PF02517: Rce1-like" amino acids 157 to 251 (95 residues), 60 bits, see alignment E=1.2e-20

Best Hits

KEGG orthology group: K07052, (no description) (inferred from 100% identity to pfs:PFLU4550)

Predicted SEED Role

"CAAX amino terminal protease family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3JXF4 at UniProt or InterPro

Protein Sequence (263 amino acids)

>PFLU_RS22305 CPBP family intramembrane metalloprotease (Pseudomonas fluorescens SBW25)
MIALPWLYLALLSIGYLLALIYGQLGILAGVSIALLLIAGYAVRQQRTPWARYLGHGLFI
VLALSLAMHWLPGFYNGRGIAPQRFTDDAVPFSMYLNQDKPLIGFWLLLACPWIVARRSL
RLSICVAALALTLTAIAALGGATLLGVISWAPKWPEQAWLWVLNNLLLVTLVEEALFRGY
VQGGLSRRFKHLPYGENLALLLASLVFGLVHIGAGWHWVLLASIAGVGYGLAYRFGGLGA
AVATHFGLNLLHFGLFTYPMLAG