Protein Info for PFLU_RS19150 in Pseudomonas fluorescens SBW25

Annotation: peptidyl-prolyl cis-trans isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 624 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details PF13624: SurA_N_3" amino acids 1 to 164 (164 residues), 154.8 bits, see alignment E=4.5e-49 PF13623: SurA_N_2" amino acids 2 to 141 (140 residues), 112.3 bits, see alignment E=4.8e-36 PF13145: Rotamase_2" amino acids 246 to 376 (131 residues), 54.4 bits, see alignment E=5.6e-18 PF13616: Rotamase_3" amino acids 256 to 361 (106 residues), 96.9 bits, see alignment E=3e-31 PF00639: Rotamase" amino acids 270 to 360 (91 residues), 97.8 bits, see alignment E=1.5e-31

Best Hits

KEGG orthology group: K03770, peptidyl-prolyl cis-trans isomerase D [EC: 5.2.1.8] (inferred from 100% identity to pfs:PFLU3925)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3JYJ6 at UniProt or InterPro

Protein Sequence (624 amino acids)

>PFLU_RS19150 peptidyl-prolyl cis-trans isomerase (Pseudomonas fluorescens SBW25)
MLQNIRDNSQGWIAKTIIGIIVALMAFTGIEAIFQASGNSKQDVAKVNGEEITQTELSQA
VDMQRRQLMQQLGKDFDASLLDEKLLREAALKSLIDRKLLLQGAADSKFGFSEAALDQVI
LQTPEFQVDGKFNAERFDQVIRQLGYSRLQFRQMLTQEMLIGQVRAGIAGSGFVTDSEVL
AFARLEKQTRDFATVNIKANPAAVKLTDDEVKAYYDQHAKEFMTPDQVVIDYLELKKSSF
FDQVAVKDDELQAAYQKETANLAEQRRAAHILIEVNDKVTDAQAKAKIEEIQARLAKGEK
FEALAKEFSQDPGSASNGGDLGFAGPGVYDPDFETALYALSKDQVSAPVRSTFGWHLIKL
LGVEAPQVPTFASLKDKLTKELKTQQVEQRFVEATKQLEDAAFEASDLAQPASDLKLTVH
TSAPFGREGGEGVAANRAVVTAAFSPEVLDEGANSTAIELDPETIIVLRAKEHLKPAQLP
LESVAAAIRTQMAKERASAAAKTHADELIASLRDGKTPLNQPVDGQAWKVTEAATRSQET
IDPAVLQALFRMPKPAAKDKPTFTTVTLADGSLVIVRLNGVNEAAAPTDEEKAQYRRFLA
SRVGQQDFAAYRKQLETKADIKKY