Protein Info for PFLU_RS17555 in Pseudomonas fluorescens SBW25

Annotation: excinuclease ABC subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 839 TIGR00630: excinuclease ABC subunit A" amino acids 139 to 823 (685 residues), 739.1 bits, see alignment E=4.4e-226 PF17755: UvrA_DNA-bind" amino acids 168 to 281 (114 residues), 47.7 bits, see alignment E=4.4e-16

Best Hits

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 70% identity to cpi:Cpin_6311)

Predicted SEED Role

"Excinuclease ABC subunit A paralog of unknown function" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3JXH2 at UniProt or InterPro

Protein Sequence (839 amino acids)

>PFLU_RS17555 excinuclease ABC subunit A (Pseudomonas fluorescens SBW25)
MTSQRTLPPITAQQHGFVRVRGAREHNLQNVDVDIPRDALVVFTGVSGSGKSSLAFSTVY
AEAQRRYFESVAPYARRLIDQVGVPDVDSIEGLPPAVALQQQRGTPSARSSVGSVTTLSS
LIRMLYSRAGSYPPGQAMLYAEDFSPNLPQGACPQCHGLGRVYEVTEALMVPDPSLTIRQ
RAVASWPLAWQGQNLRDILVTLGYDVDIPWRELPKKQRDWILFTEETPTVPVYAGFTPEQ
TREALKRKLEPSYQGTFSGARRYILHTFTHTQSALMKKRVSQYMQGSACPLCEGKRLTKA
ALSVKFAGVDIGELSQLSLAQLAELLRPVAAGQDKMKLSVEKRLAAQRIAQDLLERVSTL
TELGLGYLSLERSTPTLSSGELQRLRLATQLGSQLFGVIYVLDEPSAGLHPADGEALFTA
LERLKAAGNSLFVVEHDLETMRRADWLIDVGPAAGEHGGQVLYSGPPAGLAQVEASQTRE
YLFAEKRVANPVRREPTGWLKLEGVTRNNLDGLNVDFPLGCFTAVTGISGSGKSSLVSQA
LLELVGSGLGRVLESDEEPSLEDDTPQTSGGWISAGLEHIRRLVQVDQKPIGRTPRSNLA
TYTGLFDNVRKLFAATPAAKKRHYDAGQFSFNVAKGRCPNCEGEGFVSVELLFMPSVYAP
CPTCHGARYNPETLAIKWQGLSIAQVLGLTVEQAVEVFAEQPGVLRSLQVLRDIGLGYLR
LGQPATELSGGEAQRIKLATELQRNARGATLYVLDEPTTGLHPRDVDRLLSQLNHLVDAG
HTVVVVEHEMRVVAQSDWVIDIGPGAGDLGGKVVASGTPQKVAKSKTSRTAPFLARELI