Protein Info for PFLU_RS17330 in Pseudomonas fluorescens SBW25

Annotation: PAS domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 TIGR00229: PAS domain S-box protein" amino acids 5 to 120 (116 residues), 36.4 bits, see alignment E=2.5e-13 PF08448: PAS_4" amino acids 6 to 52 (47 residues), 24.4 bits, see alignment 7.2e-09 PF13426: PAS_9" amino acids 12 to 99 (88 residues), 30.4 bits, see alignment E=1e-10 PF00512: HisKA" amino acids 163 to 223 (61 residues), 57.9 bits, see alignment E=2.1e-19 PF02518: HATPase_c" amino acids 271 to 378 (108 residues), 73.7 bits, see alignment E=4e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU3555)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K7V5 at UniProt or InterPro

Protein Sequence (380 amino acids)

>PFLU_RS17330 PAS domain-containing sensor histidine kinase (Pseudomonas fluorescens SBW25)
MQADLFDSAACALAVTSEDGMILQANARFSEWLGFSTTELCGKRFQDLLTMGGRIFHQTH
LAPMLRMHGSVTEVKLDMLHHDGHKVTVLLNGIRREHADAVVYDLALFGTTDRDKYEREL
LNARNLSEALLQEKTAAELALKQAQAELSEAYTISQRRALFAEQMVAIVSHDLKNPLTAI
RMASDFLSRGERTPKEQQLLGHIGQSSERAQRMIADLLDFTQARVGQGIVIKATSMDLHS
VIHRTVDELRVAFPKATLEHHAIGSGNAHLDADRVQQIIGNLVANSVAYGDLQRPISITS
RLGEGRCEVSVHNHGAAIPEALLAGLFEPMTRGTDQGSDVRSVGLGLYIVRELAKVHGGD
VAVSSCATGGTTFTVTFQGT