Protein Info for PFLU_RS13380 in Pseudomonas fluorescens SBW25
Annotation: xylulokinase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 54% identical to XYLB_HAEIN: Xylulose kinase (xylB) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG orthology group: K00854, xylulokinase [EC: 2.7.1.17] (inferred from 100% identity to pfs:PFLU2740)MetaCyc: 72% identical to xylulose kinase (Pseudomonas fluorescens)
Xylulokinase. [EC: 2.7.1.17]
Predicted SEED Role
"Xylulose kinase (EC 2.7.1.17)" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization or Xylose utilization (EC 2.7.1.17)
MetaCyc Pathways
- superpathway of glucose and xylose degradation (16/17 steps found)
- D-xylose degradation I (2/2 steps found)
- xylitol degradation I (2/2 steps found)
- D-arabinitol degradation I (1/2 steps found)
- superpathway of pentose and pentitol degradation (16/42 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.7.1.17
Use Curated BLAST to search for 2.7.1.17
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See C3KAU8 at UniProt or InterPro
Protein Sequence (493 amino acids)
>PFLU_RS13380 xylulokinase (Pseudomonas fluorescens SBW25) MTQQNLYLGIDCGTQGTKAIVLDASSGKVLGLGAASHTLISGANGRREQHTQEWLDAFTE ATHRALQQAGVDGQDILGIGVSGQQHGLVLLDEHGAVLRPAKLWCDTETAAENDRLLAYL GGESGSLERLGVAIAPGYTVSKLLWTREQHPDIFARIAHILLPHDYLNYWLTGRAVAEYG DASGTGYFNVRSREWDVALLKHIDPSGRLEQALPPLIEADQAVGSILPAIAERLGINPNA IVASGGGDNMMGAIGTGNIAPGVITMSLGSSGTVYAFADQPNVSPQASVATFCSSSGGWL PLICTMNLTNATGVIRELFDLDLAAFNTLVEQAPIGADGVSMLPFLNGERVPALPHATGS LHGLTMTNLTRANLCRAVVEGTTFGLRYGLDLLRQTGLQSQSIRLIGGGSKSPVWRQMVA DIMNTEVICTEQSEAAALGAAIQAAWSQSGESLASLCDKCVSVDPASRTLPVAASVSAYQ QAYERYQQHVATL