Protein Info for PFLU_RS12565 in Pseudomonas fluorescens SBW25

Annotation: HAMP domain-containing histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 transmembrane" amino acids 18 to 38 (21 residues), see Phobius details amino acids 159 to 182 (24 residues), see Phobius details PF00672: HAMP" amino acids 182 to 233 (52 residues), 45.1 bits, see alignment 1e-15 PF02518: HATPase_c" amino acids 350 to 456 (107 residues), 79.3 bits, see alignment E=2.9e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU2571)

Predicted SEED Role

"sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K9H9 at UniProt or InterPro

Protein Sequence (464 amino acids)

>PFLU_RS12565 HAMP domain-containing histidine kinase (Pseudomonas fluorescens SBW25)
MSLLNPSKGWRSSSSRLLALYSSLFVAWSCILMGVLYYEVSGYLGDLSRHSLLQRQHLFQ
RFDGEELVEALTTSMTFDMKGVDAYGLFDEQFRPLNGPIRAMPPDLPLDGKIHALANCVD
SDDPKLPKDSCDAVATHTDDGRWLVLVRANGSLFGVTRIIWHALLWALSLTIIPGAAGWH
LLRRRPLRRIRGIQASAEAIVAGDLTHRLPLSDRRDELDMLAAIVNAMLDRIEKLMNEVK
GVCDNIAHDLRTPLTRLRAQLYRIKQEAEAESDYAVKLDDAIAETDTLMARFRGLLRISE
LEDHQRRSGFLVMDPLPLLRELHDFYLPLAEEGELQLKLEIPESLPWITGDRALLFEALA
NLLSNSIKFSPPGGEVMLRGVNDAGSTRIEVHDSGPGIPAAERDAVFQRFYRVDESDQQG
GFGLGLSIVAAIINLHGFKLEVGTSAQGGARLILECRQQLMPEA