Protein Info for PFLU_RS11595 in Pseudomonas fluorescens SBW25

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 transmembrane" amino acids 14 to 36 (23 residues), see Phobius details amino acids 42 to 60 (19 residues), see Phobius details amino acids 67 to 88 (22 residues), see Phobius details amino acids 94 to 115 (22 residues), see Phobius details amino acids 119 to 138 (20 residues), see Phobius details amino acids 144 to 165 (22 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 181 to 332 (152 residues), 91.3 bits, see alignment E=2.8e-30 PF00990: GGDEF" amino acids 182 to 329 (148 residues), 93.2 bits, see alignment E=7.6e-31

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU2361)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K959 at UniProt or InterPro

Protein Sequence (348 amino acids)

>PFLU_RS11595 GGDEF domain-containing protein (Pseudomonas fluorescens SBW25)
MPANVKLRPRMQRLLSPAIAKAELIGIFAWLAVLLVDRWAMFGWPVALVTIGLCGVYGVH
RVVTHYVLWRALGVAYMVLLSAGFAYVVHVHPALQVFALPLAVTLVLSSAILFIVVQDFL
VCAALVWLLTWPSIQMSLYEGVDIYVFIFCAASVAIGFILNVYYLKNLRSVLMVESEFRE
LAETDYLTSILNRRAFMESFSKLIAAGDTGYFMMLDIDSFKLKNDQFGHDVGDRILCAMA
ACLKSTPGSHSFGRIGGEEFGVLLVGDDPGLATDYALRLLQAIRSSVAPPHDYTCSAGMT
HFTLGADMSAVLKRADRNLYTAKGNGKDRVYLDGARVSHGSISTPEAL