Protein Info for PFLU_RS11575 in Pseudomonas fluorescens SBW25

Annotation: DeoR/GlpR transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 273 PF08279: HTH_11" amino acids 20 to 67 (48 residues), 38.4 bits, see alignment 1.3e-13 PF08220: HTH_DeoR" amino acids 20 to 75 (56 residues), 49.7 bits, see alignment E=3.6e-17 PF00455: DeoRC" amino acids 92 to 246 (155 residues), 152.1 bits, see alignment E=2e-48

Best Hits

Swiss-Prot: 42% identical to Y1009_HAEIN: Uncharacterized HTH-type transcriptional regulator HI_1009 (HI_1009) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU2357)

Predicted SEED Role

"Glycerol-3-phosphate regulon repressor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K955 at UniProt or InterPro

Protein Sequence (273 amino acids)

>PFLU_RS11575 DeoR/GlpR transcriptional regulator (Pseudomonas fluorescens SBW25)
MPTPKDTAADSSTPMIPEQRREQILRQLRKHQVMSVHQLMEMFDCSHMTVRRDIALLEQE
GRAYSVTGGVRIASQLHSEPSHQSKAVVELPQKQAMARLAARLLHADMTVYLDAGTSTLE
IVPYIKALSGMTVVTNDFGIVQALMDATQVTVIHTGGQLDHDNHSSVGGLAVATLRQIVT
DIAFVSTSSWDLHRGITTPSALKVEVKQVAMQSASQVVLVASSSKYGTFSMYRIAGLEPF
DVIISDDGLAPAAADGIRKRGIELMLPGDPLPA