Protein Info for PFLU_RS11110 in Pseudomonas fluorescens SBW25

Annotation: DUF1349 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 PF07081: DUF1349" amino acids 23 to 198 (176 residues), 225.1 bits, see alignment E=5.2e-71 PF17851: GH43_C2" amino acids 72 to 160 (89 residues), 26.4 bits, see alignment E=5.3e-10

Best Hits

Swiss-Prot: 61% identical to REE1_YEAST: Regulation of enolase protein 1 (REE1) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

KEGG orthology group: K09702, hypothetical protein (inferred from 100% identity to pfs:PFLU2261)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3KAQ0 at UniProt or InterPro

Protein Sequence (208 amino acids)

>PFLU_RS11110 DUF1349 domain-containing protein (Pseudomonas fluorescens SBW25)
MDKKQIEVASQNVEVSIWQAAKWLNEPSLYQSCADHSLEIFTDFKTDFWRETHYGFIRDS
GHFLGFETAGGFTAQVRVNADFRELYDQAGIMVRLNEETWLKAGIEYNDGMPMISSVLTQ
GTSDWAPSYFSGDPTDFWLRVTVSDGVLRLQYSTDGMTWPLLRLAPFPDAESYTVGPMCC
TPERQGLRVKFFEWSLSQPLGRDLHDLS