Protein Info for PFLU_RS10130 in Pseudomonas fluorescens SBW25
Annotation: aminopeptidase P family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 100% identity to pfs:PFLU2061)Predicted SEED Role
"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)
Isozymes
Compare fitness of predicted isozymes for: 3.4.11.9
Use Curated BLAST to search for 3.4.11.9
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See C3K527 at UniProt or InterPro
Protein Sequence (602 amino acids)
>PFLU_RS10130 aminopeptidase P family protein (Pseudomonas fluorescens SBW25) MSTQPLTHGTVPQRLAHTRELMSREGIHALLVPSADPHLSEYLPGYWQGRQWLSGFHGSV GTLIVTADFAGVWADSRYWEQASKELKGSGIELVKLQPGQPGPLEWLAEQTPEGGVVAVD GAVMAVASARTLGGKLAERGARLRTDIDLLDEVWRDRPALPNQPIYQHLPPQATVSRGEK LASLRAALKEKGADWHFIATLDDIAWLFNLRGGDVSFNPVFVSFALINQQQATLFVALSK VDAQLRGVLEQDGVTLRDYSEVADALRAVPAGASLQVDPARVTAGLLENLDAGVKLVEGL NPTTLAKSRKSLADAEHIRQAMEQDGAALCEFFAWLDSALGRERITELTIDEHLTAARTR RPGYVSLSFNTIAAYNANGAMPHYHATEEEHALIEGDGLLLIDSGGQYLGGTTDITRMVP IGTPSDEQKRDCTRVLKGVIALSRAHFPKGILSPLLDAIARAPIWAEGVDYGHGTGHGVG YFLNVHEGPQVIAYQAATAPQTAMQPGMITSIEPGTYRPGRWGVRIENLVLNREAGETEF GEFLKFETLTLCPIDTRCLEPSLLTADEREWFNAYHAHVRERLSPLLSGAALEWLQVRTA AI