Protein Info for PFLU_RS10105 in Pseudomonas fluorescens SBW25

Annotation: acyl-CoA dehydrogenase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 395 PF02771: Acyl-CoA_dh_N" amino acids 17 to 114 (98 residues), 45 bits, see alignment E=1.9e-15 PF08028: Acyl-CoA_dh_2" amino acids 236 to 370 (135 residues), 61.7 bits, see alignment E=1.4e-20 PF00441: Acyl-CoA_dh_1" amino acids 239 to 367 (129 residues), 42.1 bits, see alignment E=1.6e-14

Best Hits

Swiss-Prot: 79% identical to SFNC_PSEPU: Probable FMNH2-dependent monooxygenase SfnC (sfnC) from Pseudomonas putida

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU2056)

Predicted SEED Role

"Acyl-CoA dehydrogenase; probable dibenzothiophene desulfurization enzyme"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K523 at UniProt or InterPro

Protein Sequence (395 amino acids)

>PFLU_RS10105 acyl-CoA dehydrogenase family protein (Pseudomonas fluorescens SBW25)
MTATPHSVLPSPLQTAKLLAAEFALTAVERDERGGTPKTERDALRQSGLLALSIPAQYGG
LGARWSDTLGIVREFAKVDSSIAHVFGFHHLMLATVRLFSRPDQWQPWFEQTARKNWFWG
NALNPLDTRTVVKDFGGWREFSGKKSFCSGASDSEMLIASAVDETAGGKLLIAAIPSGRS
GITLHNDWNNIGQRQTDSGSASFERVRVEESELLLDPGPLSTPFACLRPLIAQLTFTHMF
LGIAEGAFEEARNYTLTETRSWHKSSAEDVRQDPYVLHHYGEFWVALEGVRLLVERAAEL
LDHAWAKGPNLSESERGQLAIAIATAKVAATRQGLDLCSRLFEVTGARATHASLRLDRHW
RNLRTQTLHDPVDYKLHELGDWALNQSLPIPTFYS