Protein Info for PFLU_RS07625 in Pseudomonas fluorescens SBW25

Annotation: ABC transporter ATP-binding protein/permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 592 signal peptide" amino acids 1 to 43 (43 residues), see Phobius details transmembrane" amino acids 66 to 88 (23 residues), see Phobius details amino acids 140 to 159 (20 residues), see Phobius details amino acids 165 to 183 (19 residues), see Phobius details amino acids 246 to 267 (22 residues), see Phobius details amino acids 281 to 300 (20 residues), see Phobius details TIGR02204: ABC transporter, permease/ATP-binding protein" amino acids 6 to 581 (576 residues), 907.7 bits, see alignment E=1.6e-277 PF00664: ABC_membrane" amino acids 27 to 293 (267 residues), 176.3 bits, see alignment E=1.1e-55 PF00005: ABC_tran" amino acids 362 to 510 (149 residues), 113.8 bits, see alignment E=1e-36

Best Hits

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 100% identity to pfs:PFLU1548)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K608 at UniProt or InterPro

Protein Sequence (592 amino acids)

>PFLU_RS07625 ABC transporter ATP-binding protein/permease (Pseudomonas fluorescens SBW25)
MFSVRQRRAIRLASRFIAPYRWHALGALLALIVTAGITLSMGQGIRLLVDQGFMTQSPHL
LNQSIGLFMVLVLGLAVGTFARFYLVSWIGERVVADIRRQVFNHLIYLHPGFYENNRSSE
IQSRLTTDTTLLQSVIGSSLSLFLRNALMVIGGIVLLFVTNPKLTSIVVVALPLVLAPIL
IFGRRVRSLSRQSQDRIADVGSYVSETLGQIKTVQAYNHQVQDEQRFAVTVEDAFTTARK
RITQRAWLITLVIMLVLGAVGVMLWVGGMDVISGRISGGELAAFVFYSLIVGSAVGTLSE
VLGELQRAAGAAERIGELLQSSNDIQAPADGTVQLPERVSGRMELQDLRFSYPSRPDSYA
IDGLNLTINPGETLALVGPSGAGKSTIFDLLLRFYDPQQGRILLEGHPLTELDPMDLRRH
FALVSQSPALFFGSVEENIRYGNPTATTEQVEAAARIAHAHDFILQMPDGYQTHLGDGGM
GLSGGQRQRLAIARALLVDAPILLLDEATSALDAQSEHLIQQALPQLMQGRTTLVIAHRL
ATVKNADRIAVMDQGKLVAVGTHQQLIASNPLYARLAALQFSDGAEGAESED