Protein Info for PFLU_RS05880 in Pseudomonas fluorescens SBW25

Annotation: CinA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 PF02464: CinA" amino acids 5 to 156 (152 residues), 175.9 bits, see alignment E=2.3e-56 TIGR00199: amidohydrolase, PncC family" amino acids 11 to 157 (147 residues), 143.2 bits, see alignment E=3.3e-46

Best Hits

Swiss-Prot: 76% identical to PNCC_PSEPU: Nicotinamide-nucleotide amidohydrolase PncC (pncC) from Pseudomonas putida

KEGG orthology group: K03743, (no description) (inferred from 100% identity to pfs:PFLU1188)

Predicted SEED Role

"C-terminal domain of CinA type S; Protein Implicated in DNA repair function with RecA and MutS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3KDF9 at UniProt or InterPro

Protein Sequence (166 amino acids)

>PFLU_RS05880 CinA family protein (Pseudomonas fluorescens SBW25)
MKEITQLAAELGRRLQVLNAHVTTAESCTGGGIAEAITRVPGSSAWFEAGYVTYSNRQKT
RQLNVPETLFPKVGAVSQEVVEAMVRGAQEKSLARFAVAVSGVAGPDGGSPDKPVGTVWL
AFGVGDELTAELQHFPGNRDEVRRQTVKAALEGLLRRAAAEIENQG