Protein Info for PFLU_RS05180 in Pseudomonas fluorescens SBW25

Annotation: PepSY domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 524 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 143 to 163 (21 residues), see Phobius details amino acids 188 to 213 (26 residues), see Phobius details amino acids 342 to 364 (23 residues), see Phobius details amino acids 385 to 404 (20 residues), see Phobius details amino acids 418 to 436 (19 residues), see Phobius details amino acids 447 to 466 (20 residues), see Phobius details amino acids 478 to 499 (22 residues), see Phobius details PF03929: PepSY_TM" amino acids 10 to 365 (356 residues), 250.8 bits, see alignment E=1.3e-78

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU1044)

Predicted SEED Role

"FIG138928: iron-regulated membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3K6F4 at UniProt or InterPro

Protein Sequence (524 amino acids)

>PFLU_RS05180 PepSY domain-containing protein (Pseudomonas fluorescens SBW25)
MKEGFRQAMAWLHTWAGLIFGWLLFAIFLTGTLAYFKDEISHWMQPEVQAHPLDDTRSLT
VAQAYLQQQAPNAARWFITLPDSRDPGLSVMWQDKVDPGKRGNFIQKTLDPVSGQAVQAR
ESMGGEFFYRFHFQLQMPHPWGRWLSTIAAMVMFVALITGIITHKKIFKDFFTFRPRKGQ
RSWLDGHNAVGVLVLPFHLMITYSSLVIFMSMVMPAPILASYGNDTRAFFSEVFPNTNNA
PALGQPGTLRPLVPMYEQARAQWDGGHVGRVAVNNPSDVNASVNVFRAGSDSVVHDFGST
VSFNGSTGELLRVSGEQSLPAAIGGSFYGLHMGHFAGPVLRWLYFICGLAGTAMIGTGLV
IWLGKRQLKHAKAAVMPFELRLVEVLNIASMSGLMIAIAVFFWANRLLPVSFAERSDWEV
QTFFIAWGLSLLHAILRRGRQGWVEQLSVGALLFIAIPLLNALTTSHHLGVSLATGDWAM
AGFDLTCLASGVFLAWAAWKMQHRTAPAPKAERARPLTLKQETN