Protein Info for PFLU_RS01245 in Pseudomonas fluorescens SBW25

Annotation: taurine dioxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02668: TauD
  • amino acids 6 to 271 (266 residues), 245.9 bits, E=3.7e-77

Best Hits

Swiss-Prot: 61% identical to TAUD_ECOLI: Alpha-ketoglutarate-dependent taurine dioxygenase (tauD) from Escherichia coli (strain K12)

KEGG orthology group: K03119, taurine dioxygenase [EC: 1.14.11.17] (inferred from 100% identity to pfs:PFLU0252)

MetaCyc: 61% identical to taurine dioxygenase (Escherichia coli K-12 substr. MG1655)
Taurine dioxygenase. [EC: 1.14.11.17]

Predicted SEED Role

"Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17)" in subsystem Alkanesulfonate assimilation or Taurine Utilization (EC 1.14.11.17)

MetaCyc Pathways

• taurine degradation IV (1/1 steps found)
• superpathway of taurine degradation (2/6 steps found)

KEGG Metabolic Maps

• Taurine and hypotaurine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.14.11.17

Use Curated BLAST to search for 1.14.11.17

Sequence Analysis Tools

See C3KE52 at UniProt or InterPro

Protein Sequence (278 amino acids)

>PFLU_RS01245 taurine dioxygenase (Pseudomonas fluorescens SBW25)
MSSLTVTPLSTALGAQISGVDITQPLDLEQRHAIEQALLTHSVLFFRGQAINPQQQARFA
ANFGDLHIHPIYPNVPEQPEVLILDTAVTDVRDNAVWHTDVTFLPTPALGAVLSAKLLPA
FGGDTLWASGIAAYEALSEPFKRLLDGLTATHDFTKSFPLERFGNTAEDLVRWEETRKKN
PPLSHPVVRTHPVSGRKSLFVSDGFTTKINELEPAESEAILKLLFAHATRPEFTIRWRWQ
ENDVAFWDNRVTQHYAVDDYRPQRRVMHRATILGDIPF