Protein Info for PFLU_RS00835 in Pseudomonas fluorescens SBW25

Annotation: VWA domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 540 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details PF12450: vWF_A" amino acids 78 to 168 (91 residues), 130.6 bits, see alignment E=4.2e-42 PF00092: VWA" amino acids 185 to 350 (166 residues), 79.1 bits, see alignment E=1.2e-25 PF13768: VWA_3" amino acids 185 to 342 (158 residues), 35.4 bits, see alignment E=2.8e-12 PF13519: VWA_2" amino acids 186 to 290 (105 residues), 56.4 bits, see alignment E=1.1e-18 PF12034: YfbK_C" amino acids 361 to 538 (178 residues), 230.5 bits, see alignment E=4.1e-72

Best Hits

KEGG orthology group: K07114, uncharacterized protein (inferred from 100% identity to pfs:PFLU0165)

Predicted SEED Role

"Von Willebrand factor type A domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See C3KBG6 at UniProt or InterPro

Protein Sequence (540 amino acids)

>PFLU_RS00835 VWA domain-containing protein (Pseudomonas fluorescens SBW25)
MSRPLLFLRPAAQGFAVTMVVALAGCGLSSSPELAKPAEPVAELQTASPQGALVKRMAMP
APMRMQESAAMDYRSEPREQYANLPDNPVHRVAETPVSTFSVDVDTGSYANVRRFLNQGS
LPPEGAVRLEEMVNYFPYHYALPTDGSPFGVTTEVAATPWNPRTQLLRIGIKASDRPVAE
LAPANLVFLVDVSGSMDRREGLPLVKSTLKLLVDQLREQDRVSLVVYAGESRVVLKPTSG
RDKVKIRNAIDQLTAGGSTAGASGIELAYQMAREGFIDNGINRILLATDGDFNVGISDFD
SLKQMAVEQRKSGVSLTTLGFGVDNYNEHLMEQLADAGDGNYAYIDNLREAHKVLVDQLS
STLAVVARDVKLQVEFNPAQVSEYRLLGYENRALKREDFNNDKVDAGEIGAGHTVTALYE
IVPKGEKGWSEPLRYAAAPAAEDKSGELAMLRVRYKSAAGGDSQLIERPIRNKSTQASDD
LRFAAAVAAFAQQLKGDGRYTGSMSLQDTAELARSARGNDPFGLRNEFVQLVELAQSLKP