Protein Info for OLJFJH_07835 in Erwinia amylovora T8

Annotation: citrate-proton symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 transmembrane" amino acids 26 to 43 (18 residues), see Phobius details amino acids 53 to 77 (25 residues), see Phobius details amino acids 89 to 110 (22 residues), see Phobius details amino acids 119 to 143 (25 residues), see Phobius details amino acids 155 to 177 (23 residues), see Phobius details amino acids 189 to 209 (21 residues), see Phobius details amino acids 237 to 258 (22 residues), see Phobius details amino acids 278 to 295 (18 residues), see Phobius details amino acids 307 to 327 (21 residues), see Phobius details amino acids 340 to 358 (19 residues), see Phobius details amino acids 370 to 393 (24 residues), see Phobius details amino acids 405 to 424 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 22 to 434 (413 residues), 114.4 bits, see alignment E=6.4e-37 PF07690: MFS_1" amino acids 23 to 384 (362 residues), 113.8 bits, see alignment E=8.8e-37 amino acids 279 to 420 (142 residues), 36.6 bits, see alignment E=2.7e-13

Best Hits

Swiss-Prot: 60% identical to CITH_KLEPN: Citrate-proton symporter (citH) from Klebsiella pneumoniae

KEGG orthology group: None (inferred from 100% identity to eam:EAMY_0471)

MetaCyc: 58% identical to propane-1,2,3-tricarboxylate-proton symporter (Salmonella enterica enterica serovar Typhimurium str. LT2)
RXN1R65-49

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (440 amino acids)

>OLJFJH_07835 citrate-proton symporter (Erwinia amylovora T8)
MTSHVTQPVSRQSGARRIFNVTSGNFLEMYDFMVFGYYATAIAKTFFPGDDPFASLMLTL
MTFGAGFLMRPLGAIILGSYIDRHGRRKGLLLTLGLMALGTLSIAITPGYSTLGMAAPIM
ILLGRLLQGFSAGVELGGVSVYLSEIAPKGRKGFYVSWQSASQQIAVIFAALLGLMLNHL
LDKGEVTDWGWRVPFLIGCLIVPFLFWIRRMLEETEAFSQRKHHPSMRQIVHSVGRNWAL
VLAGMLMVVTTTVMFYMITAYTPTFGKTVLMISDKQSFLVTLCVGISNLFWLPVMGSLSD
RIGRRPLLLLFTVLMIATAWPVLNWLVGSPSLTHLLLAELWLSFLYGSYNGAMVVYLAEV
MPAEVRATGFSLAYSLATALFGGFTPAVCSYLIHVTGDKAMPGVWLSFAAVCGLLGTLII
KRLVKQYQARRLMEPAIQLP