Protein Info for OLJFJH_07360 in Erwinia amylovora T8

Annotation: MFS transporter family glucose-6-phosphate receptor UhpC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 transmembrane" amino acids 26 to 45 (20 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details amino acids 97 to 127 (31 residues), see Phobius details amino acids 154 to 177 (24 residues), see Phobius details amino acids 185 to 203 (19 residues), see Phobius details amino acids 250 to 269 (20 residues), see Phobius details amino acids 289 to 309 (21 residues), see Phobius details amino acids 320 to 339 (20 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 378 to 400 (23 residues), see Phobius details amino acids 411 to 431 (21 residues), see Phobius details TIGR00881: phosphoglycerate transporter family protein" amino acids 36 to 413 (378 residues), 434.9 bits, see alignment E=1.3e-134 PF07690: MFS_1" amino acids 36 to 396 (361 residues), 188.3 bits, see alignment E=9.8e-60

Best Hits

Swiss-Prot: 60% identical to UHPC_ECOLI: Membrane sensor protein UhpC (uhpC) from Escherichia coli (strain K12)

KEGG orthology group: K07783, MFS transporter, OPA family, sugar phosphate sensor protein UhpC (inferred from 100% identity to eam:EAMY_0372)

MetaCyc: 36% identical to sn-glycerol 3-phosphate:phosphate antiporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-22

Predicted SEED Role

"Hexose phosphate uptake regulatory protein UhpC" in subsystem Hexose Phosphate Uptake System

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (445 amino acids)

>OLJFJH_07360 MFS transporter family glucose-6-phosphate receptor UhpC (Erwinia amylovora T8)
MIKWIKSAPEQPLLADKEHVDDTYRYWRIQIMLGMYVGYAVYYLTRKSFNYVMPEMLQDL
GFTIADVGLISTLFYFMYGASRFISGVLSDAANPRYFMGIGLILTGVLNILFGVSSSLFA
LIVLWIANAFFQGWGWAPCAKLLTSWYSRNERGFWWAACNTSHNVGGAVIPLLAGVLAVH
HGWRYGMIVPGVIAIISGCFLCFRLRDRPASMGLPSVGRWRSDSQELDQEQKSAKLPLML
MLKKYIFFNKYIWLLATSYVFVYVVRIGINDWGNLYLTQNHGFSLVKANSALTMLEVGGF
IGTIVAGWGSDKLFAGNRVPMNIIFMIGILLSVLLIWLLRIDSYVFNAICFFFIGFFIFG
PQMLIGMAAAESSHKNSAGAATGFVGIFGYLGAALSGWPLAKVLESWSWDGFFVVLSVTT
LASTLLLLPLAIEPRRAKPEAADES