Protein Info for OLJFJH_04580 in Erwinia amylovora T8

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 273 PF00561: Abhydrolase_1" amino acids 21 to 254 (234 residues), 125.2 bits, see alignment E=1.1e-39 PF12697: Abhydrolase_6" amino acids 23 to 261 (239 residues), 79 bits, see alignment E=2.5e-25 PF12146: Hydrolase_4" amino acids 23 to 122 (100 residues), 46.5 bits, see alignment E=8.8e-16 amino acids 203 to 253 (51 residues), 28.2 bits, see alignment 3.5e-10 PF01738: DLH" amino acids 205 to 260 (56 residues), 24.8 bits, see alignment E=4.6e-09 PF00326: Peptidase_S9" amino acids 209 to 272 (64 residues), 25.9 bits, see alignment E=2e-09

Best Hits

Swiss-Prot: 73% identical to ESTE_PSEFL: Arylesterase from Pseudomonas fluorescens

KEGG orthology group: None (inferred from 100% identity to eay:EAM_3337)

Predicted SEED Role

"Non-heme chloroperoxidase (EC 1.11.1.10)" (EC 1.11.1.10)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.11.1.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (273 amino acids)

>OLJFJH_04580 alpha/beta hydrolase (Erwinia amylovora T8)
MSTFKTQDGTQLYYKDWGSGKPVLFSHGWPLNADMWDSQMNFLAERGYRVIAFDRRGFGR
SDQPWEGYNYDTFASDINDLITHLDLHEVTLVGFSMGGGDVSRYIGRYGSGRVSALALLG
AVTPIFGQTADHPEGVEKSVFDGIRAGLRKDRAQFISEFSTPFYGTNAGQTVSQGVLTQT
LNIALLASLKGTIDCVTAFAESDFRADIAKIDVPTLVIHGSNDQVVPFEATGKLSARMIN
NAELKVYDNAPHGFAVTHQDQLNQDLLAFLQQR