Protein Info for OKGIIK_16770 in Rhodanobacter sp. FW510-T8

Annotation: Heme biosynthesis protein HemY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 42 to 65 (24 residues), see Phobius details TIGR00540: heme biosynthesis-associated TPR protein" amino acids 9 to 377 (369 residues), 237.8 bits, see alignment E=8.5e-75 PF07219: HemY_N" amino acids 29 to 128 (100 residues), 80.6 bits, see alignment E=3.1e-26 PF13176: TPR_7" amino acids 353 to 384 (32 residues), 16.2 bits, see alignment (E = 3.2e-06)

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (418 amino acids)

>OKGIIK_16770 Heme biosynthesis protein HemY (Rhodanobacter sp. FW510-T8)
MKLWYGIGLLVVAAALAAFGWHWVVADPGYVLLRLRGWRVETTVVAAVVILLLAWVLLTL
LWRLARWPFGAFSRRHRRLSQQRLGEGLLALAEGRHGDAERDLNRASRLGSLHGPALLAA
AEAASRRGEHGRALEALDQAAQSAPQAARVLRARVLRREGKPAEALALLAPESDKGTLTP
GGWRELARAALATGDLRRAREALAPLQKSGALGNRAYAALEARVLAATIQAAPDGASLNT
LWSQLPKTQRRVPAVIDAYARRAAAFGLTLPAMDEVESALRREWSPLLVETYGTLAGDDI
EARLRRAEGWLDAHPNDANLLLTLGRMCVRLELWGKARQYLQRSLALAPGAGAWEALGDA
FAGQGDAQQAQRCYRNALAFARGDAVVALASAANPLQPDTRPIALEERDVHGVPRLRE