Protein Info for OKGIIK_15045 in Rhodanobacter sp. FW510-T8

Annotation: 1-acyl-sn-glycerol-3-phosphate acyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 266 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 62 to 77 (16 residues), see Phobius details PF01553: Acyltransferase" amino acids 84 to 196 (113 residues), 92.9 bits, see alignment E=7.7e-31

Best Hits

KEGG orthology group: K00655, 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC: 2.3.1.51] (inferred from 50% identity to sml:Smlt0144)

MetaCyc: 57% identical to lysophosphatidylcholine acyltransferase (Xanthomonas campestris pv. campestris)
1-acylglycerophosphocholine O-acyltransferase. [EC: 2.3.1.23]

Predicted SEED Role

"1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria or Phosphate metabolism (EC 2.3.1.51)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.51

Use Curated BLAST to search for 2.3.1.23 or 2.3.1.51

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (266 amino acids)

>OKGIIK_15045 1-acyl-sn-glycerol-3-phosphate acyltransferase (Rhodanobacter sp. FW510-T8)
MSTDTASVPERDPLRPLRYLWRVPLVLLHIVLGVALCALVLSWNQQAVMKDGREPFAHRM
IRWWSVSLLRIIGLRSVRFGQPLRDPVLFVANHTSWIDIVMLHSQRAACFVAKAEIAGWP
LVGWLASNGGTIFHRRGSNHSLSTVMQAMVERLRAGRSVAVFPEGGTGYNGVLKVFHARI
FQAALDAEVPVQPVALRFARAGRRVIDAGFRENESFVHNIVRMLGEAPLDAEVRFLAPVP
ATPEARRRMAELSRERIAAALEVHPG