Protein Info for OKGIIK_13945 in Rhodanobacter sp. FW510-T8

Annotation: Dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF01266: DAO" amino acids 2 to 261 (260 residues), 34.7 bits, see alignment E=2.2e-12 PF13450: NAD_binding_8" amino acids 5 to 74 (70 residues), 54.4 bits, see alignment E=1.8e-18 PF01593: Amino_oxidase" amino acids 10 to 262 (253 residues), 67.3 bits, see alignment E=2.5e-22

Best Hits

KEGG orthology group: K06954, (no description) (inferred from 67% identity to xac:XAC1377)

MetaCyc: 42% identical to (E)-11-methyl-12-octadec-12-enoate hydroxylase/cyclase (Cereibacter sphaeroides)
RXN-16881

Predicted SEED Role

"COG2907: Amine oxidase, flavin-containing"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (432 amino acids)

>OKGIIK_13945 Dehydrogenase (Rhodanobacter sp. FW510-T8)
MRIAVVGSGIAGLASAWLLSRQHEVTLFEANSYFGGHTHTHAVEQAGRRYRIDSGFIVHN
PAHYPLLTQMFAQLGVASQPTTMSFSVHSEASGLEYNAATLDTLFCQRRNLLSPRFLGMV
RDLARFYREAPALLSQRDDATTLGAYLDQHRYGAAFRDEHLVPMASALWSSPPTQILQFP
ARYLVQFMANHQMLQLSDRPQWRVVKDGSSTYVAALRAHWPVRERLNCPVFSIRRQHDGV
EVDSAAGTERFEQIVLACHSDQSLALLADASEREQSILGAIAWQANDTVLHTDASVLPRR
RKAWAAWNAWLPRDADAACTVSYCMNLLQGIDSPEPFVVTLNRTAAIDPDKVLACMRYHH
PVYTRASVQAQARKAEIQGARRTWFAGAWWGWGFHEDGMRSAVEVAAALGVHWPLRTGPM
PATMAREAELVA