Protein Info for OKGIIK_12920 in Rhodanobacter sp. FW510-T8

Name: ctpA
Annotation: C-terminal processing protease CtpA/Prc, contains a PDZ domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF22694: CtpB_N-like" amino acids 54 to 112 (59 residues), 45.3 bits, see alignment E=2.5e-15 TIGR00225: C-terminal processing peptidase" amino acids 78 to 391 (314 residues), 329.2 bits, see alignment E=1.4e-102 PF00595: PDZ" amino acids 122 to 193 (72 residues), 39.4 bits, see alignment E=1.6e-13 PF13180: PDZ_2" amino acids 127 to 205 (79 residues), 45.8 bits, see alignment E=1.6e-15 PF17820: PDZ_6" amino acids 141 to 193 (53 residues), 38.3 bits, see alignment 2.3e-13 PF03572: Peptidase_S41" amino acids 226 to 388 (163 residues), 170.9 bits, see alignment E=4.5e-54

Best Hits

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 49% identity to nwa:Nwat_0028)

Predicted SEED Role

"Carboxyl-terminal protease (EC 3.4.21.102)" (EC 3.4.21.102)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.102

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (464 amino acids)

>OKGIIK_12920 C-terminal processing protease CtpA/Prc, contains a PDZ domain (Rhodanobacter sp. FW510-T8)
MRPSPRRPFALLLAVPFLLLAVPGARAQSAPAGAGTAAPPANLPAATSSAAAPASASSAD
QVDLDDIRNFSRVYEVVRQAYVEKVDNKTLMKAAITGMLSGLDPHSEYLDKDGLTQLNED
TTGEYSGLGIEVLQVDGGLRIVSPIDDTPAARAGIKPGDSIVKVNGTVVDTQNVDEMFKQ
LRGKPGSKIDLTIVHQNSDKLIDLHLVRENIAISSVKVRELEPGYVYVRVSQFQSDTATD
LEKKLGQLIAKNGPPKGAVLDLRNNPGGLLTAAVGVSDDFLDAGTIVTTRGRLQDANMSF
SAHPGDQLAGAPMIVLTNNGTASAAEIVSGALKDNHRALIMGQRTFGKGVVQTVLPLDAD
HAVKITTARYYTPNGTSIQAEGIKPDIALADLSVNPSDRGPVLISSEADLPNHLANEKAK
AGSDINDDGSAADAKLATSDYALSQALNVLKGMALRQPAGAARR