Protein Info for OKGIIK_12525 in Rhodanobacter sp. FW510-T8

Annotation: D-galactose transporter GalP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 signal peptide" amino acids 16 to 16 (1 residues), see Phobius details transmembrane" amino acids 17 to 38 (22 residues), see Phobius details amino acids 58 to 79 (22 residues), see Phobius details amino acids 87 to 105 (19 residues), see Phobius details amino acids 111 to 133 (23 residues), see Phobius details amino acids 144 to 162 (19 residues), see Phobius details amino acids 174 to 193 (20 residues), see Phobius details amino acids 254 to 276 (23 residues), see Phobius details amino acids 290 to 312 (23 residues), see Phobius details amino acids 320 to 342 (23 residues), see Phobius details amino acids 350 to 374 (25 residues), see Phobius details amino acids 393 to 413 (21 residues), see Phobius details amino acids 419 to 437 (19 residues), see Phobius details TIGR00879: MFS transporter, sugar porter (SP) family" amino acids 6 to 448 (443 residues), 434.7 bits, see alignment E=2.2e-134 PF00083: Sugar_tr" amino acids 21 to 451 (431 residues), 428.9 bits, see alignment E=5.1e-132 PF07690: MFS_1" amino acids 25 to 290 (266 residues), 95.5 bits, see alignment E=6.4e-31 amino acids 265 to 448 (184 residues), 39.9 bits, see alignment E=5.2e-14 PF13347: MFS_2" amino acids 239 to 377 (139 residues), 27.3 bits, see alignment E=2.7e-10

Best Hits

Swiss-Prot: 69% identical to GALP_ECOL6: Galactose-proton symporter (galP) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K08137, MFS transporter, SP family, galactose:H+ symporter (inferred from 69% identity to aca:ACP_2530)

MetaCyc: 69% identical to galactose:H+ symporter (Escherichia coli K-12 substr. MG1655)
RXN0-7077; TRANS-RXN-21

Predicted SEED Role

"Arabinose-proton symporter" in subsystem L-Arabinose utilization

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (463 amino acids)

>OKGIIK_12525 D-galactose transporter GalP (Rhodanobacter sp. FW510-T8)
MNTHVIAAPAMQSRTTVVFTCVLAALAGLMFGLDIGVISGATQFIQNDFSVSDHVIEWIV
SSMMFGAAVGAVGASWLSAALGRKRSLILGAVLFVLGSLLSGLAWSPDTLIAARLVLGLA
IGVATFTAPLYLAEVAPERIRGAMISTYQLMITIGILVAFLSDTALSYTGAWRWMLGVIA
IPGALFLLGVLLLPDSPRWLMMRGRRDEAIGVLRRLRGDEAVVLREAADIEEQLRTPQRG
WHLFLENRNFRRSVGLGVLLQLMQQFTGMNVVMYYAPRIFQTMGYDTAAQMWFTALVGLT
NVLATFIAIALIDRWGRKPILYTGFAVMAAGLGVVGAMMHGGIGSHAEQIFTVAMLLMFI
VGFAMSAGPLVWTLCSEIQPLKGRDFGIGCSTFTNWIANMIVGATFLSLLNGIGNAHTFW
LYASLNILFIGLTLWLVPETKGVTLEQIERNLMHGKPLREIGR