Protein Info for OKGIIK_12240 in Rhodanobacter sp. FW510-T8

Annotation: chloride channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 631 transmembrane" amino acids 49 to 79 (31 residues), see Phobius details amino acids 99 to 118 (20 residues), see Phobius details amino acids 196 to 221 (26 residues), see Phobius details amino acids 232 to 250 (19 residues), see Phobius details amino acids 262 to 286 (25 residues), see Phobius details amino acids 306 to 330 (25 residues), see Phobius details amino acids 342 to 362 (21 residues), see Phobius details amino acids 372 to 393 (22 residues), see Phobius details amino acids 404 to 427 (24 residues), see Phobius details amino acids 433 to 454 (22 residues), see Phobius details PF00654: Voltage_CLC" amino acids 110 to 450 (341 residues), 284.1 bits, see alignment E=1.6e-88 PF00571: CBS" amino acids 485 to 540 (56 residues), 25.3 bits, see alignment 1.5e-09 amino acids 550 to 604 (55 residues), 48.4 bits, see alignment 9.6e-17

Best Hits

KEGG orthology group: None (inferred from 60% identity to scl:sce0443)

Predicted SEED Role

"Chloride channel protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (631 amino acids)

>OKGIIK_12240 chloride channel protein (Rhodanobacter sp. FW510-T8)
MTASENEPGRPAVQTEGSTDALPLAPTMGMSLDAAKMPRRSTLVDRRVLRITAVSIVLGV
LAALIAKLLTALIGVVTNLAFYGRWSTAFSSPADAVPHLGWWVVLVPVAGGLIVGVMARW
GSRAIRGHGIPEAMEQVLLNESKIPPRITFLKPISSAIAIGTGGPFGAEGPIIATGGALG
SFIGQVLKVTGSERKVLLAAGAAAGMAAVFSAPIAAVVLAVELLLFELRPRSLIPVALAC
VAATGMRYLLQGTTPVFQMPVLAAPGAMALFLYVLIGALIGVVSVWTTRLVYGIEDWFEK
LPIHWMWWPALGGVVVGVVGYFAPLTLGVGYTNIENILNGRLTLAALAFLCVMKFLSWSI
ALGSGTSGGTLAPLFTIGGALGASIGIGIAALAPQIGMDPRIAALVGMAAIFAGASRALL
TAVVFAFETTGQPVGLLPLLGGCTAAYLISALMMRNTIMTEKIVRRGVRVPSEYVADYLD
QVGVDEACSRNVVTLKASQTLAEVRRWLAEELPQAQHQGYPVVDERGHVQGVLTRRSLLD
PQWHYTLTLSELVTRPPIAVSESHSLREAADHMVAESVGRLVVVSKDDPHKLVGIITRGD
ILAAHARRLREARHSARYLRFRDGLKPRPAP