Protein Info for OKGIIK_11750 in Rhodanobacter sp. FW510-T8
Annotation: Dimethylmenaquinone methyltransferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 40% identical to GLCD_BACSU: Glycolate oxidase subunit GlcD (glcD) from Bacillus subtilis (strain 168)
KEGG orthology group: K03777, D-lactate dehydrogenase [EC: 1.1.1.28] (inferred from 62% identity to tgr:Tgr7_0755)Predicted SEED Role
"Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD" in subsystem Glycolate, glyoxylate interconversions or Photorespiration (oxidative C2 cycle) (EC 1.1.99.14)
MetaCyc Pathways
- heterolactic fermentation (15/18 steps found)
- superpathway of glucose and xylose degradation (14/17 steps found)
- L-alanine degradation II (to D-lactate) (3/3 steps found)
- glycolate and glyoxylate degradation II (2/2 steps found)
- mixed acid fermentation (12/16 steps found)
- pyruvate fermentation to (R)-lactate (1/1 steps found)
- vancomycin resistance I (2/3 steps found)
- glycolate and glyoxylate degradation I (2/4 steps found)
- glycolate and glyoxylate degradation III (1/3 steps found)
- photorespiration I (5/9 steps found)
- photorespiration III (5/9 steps found)
- superpathway of glycol metabolism and degradation (3/7 steps found)
- photorespiration II (5/10 steps found)
- L-alanine degradation VI (reductive Stickland reaction) (2/6 steps found)
- superpathway of L-alanine fermentation (Stickland reaction) (4/9 steps found)
- superpathway of fermentation (Chlamydomonas reinhardtii) (4/9 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.1.1.28 or 1.1.99.14
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (457 amino acids)
>OKGIIK_11750 Dimethylmenaquinone methyltransferase (Rhodanobacter sp. FW510-T8) MTLPATLLDRLRAIFPGGELSTSDAVRNECAHDNSRYRALPELVVFPTGHDQVEALVRAC REHRVPLTARGGGTSSTGASVPMAGGVVANFMRMNRILRIDPDNRLAVVEPGVSNEALQQ ALAPYGFFWAPDPGSAPWCTVGGNLACNASGPHAVKYGSTRDNVLGLAAVAGSGKSFRCG THTTKSAIGYDLTRLVVGSEGTLAVITEATLKLTPRPAAVRTLRATYRDVASAARAVTRI MAQPATPCALEFMDALALKLARDHQPEAGVPAAEALLMIELDGAPDTLDGATAAIEAAAR VDGLVQLEVARDEAQTRALWAARKALSLAQRSVTQHKINEDVVVPVSRLPELVDGVRALS EKHAVPIVSFGHAGNGNLHVNLLPRDVDEIERAYAALPELFALVLALDGTISGEHGIGVV KREFMPLALEPATLELMRNIKAAFDPDGILNPGKLLP