Protein Info for OKGIIK_10925 in Rhodanobacter sp. FW510-T8

Name: cysW
Annotation: sulfate ABC transporter permease subunit CysW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 291 transmembrane" amino acids 21 to 46 (26 residues), see Phobius details amino acids 67 to 94 (28 residues), see Phobius details amino acids 105 to 130 (26 residues), see Phobius details amino acids 145 to 165 (21 residues), see Phobius details amino acids 205 to 231 (27 residues), see Phobius details amino acids 251 to 271 (21 residues), see Phobius details TIGR02140: sulfate ABC transporter, permease protein CysW" amino acids 24 to 279 (256 residues), 407.5 bits, see alignment E=2.5e-126 TIGR00969: sulfate ABC transporter, permease protein" amino acids 27 to 278 (252 residues), 327.3 bits, see alignment E=7.8e-102 PF00528: BPD_transp_1" amino acids 87 to 278 (192 residues), 45.2 bits, see alignment E=4.6e-16

Best Hits

Swiss-Prot: 52% identical to CYSW_ECOLI: Sulfate transport system permease protein CysW (cysW) from Escherichia coli (strain K12)

KEGG orthology group: K02047, sulfate transport system permease protein (inferred from 74% identity to rso:RSc1346)

MetaCyc: 52% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysW (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysW" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (291 amino acids)

>OKGIIK_10925 sulfate ABC transporter permease subunit CysW (Rhodanobacter sp. FW510-T8)
MNAHASAPASTRPPDWPRRLLRGALVLVAVGFMVLFLLLPLATVFVEALRAGMHAYLASI
RQPEALAAIRLTLLVAAIAVPLNLVFGVAAAWLMARFEFRGKALLGALIDLPFSVSPVIA
GLVYVLLFGAQGWFGPWLDARGVRVVFAVPGLVLATVFITLPFVARELIPLMQAQGSEEE
QAARVLGANGWQMFFRVTLPNIRWALLYGVLLCNARAMGEFGAVSVVSGHIRGLTTTMPL
EVEMRYNEYDFAGAFAVASLLALLALVTLAVKTLLEWRYGNEIAAHAPGGH