Protein Info for OKGIIK_09105 in Rhodanobacter sp. FW510-T8

Name: mfd
Annotation: transcription-repair coupling factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1194 PF17757: UvrB_inter" amino acids 131 to 219 (89 residues), 92.9 bits, see alignment 3.9e-30 PF21132: MFD_D3" amino acids 375 to 416 (42 residues), 45.9 bits, see alignment (E = 1.6e-15) TIGR00580: transcription-repair coupling factor" amino acids 469 to 1124 (656 residues), 973.5 bits, see alignment E=7.1e-297 PF02559: CarD_TRCF_RID" amino acids 523 to 579 (57 residues), 65.9 bits, see alignment 9.3e-22 PF04851: ResIII" amino acids 647 to 804 (158 residues), 40.7 bits, see alignment E=8.6e-14 PF00270: DEAD" amino acids 648 to 810 (163 residues), 89.5 bits, see alignment E=7.7e-29 PF00271: Helicase_C" amino acids 846 to 952 (107 residues), 69.5 bits, see alignment E=1e-22 PF03461: TRCF" amino acids 1052 to 1144 (93 residues), 96.9 bits, see alignment 2.5e-31

Best Hits

Predicted SEED Role

"Transcription-repair coupling factor" in subsystem DNA-replication or Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1194 amino acids)

>OKGIIK_09105 transcription-repair coupling factor (Rhodanobacter sp. FW510-T8)
MPSPIKHPPLPTTPRQRRYWTPPHGSARALLLAEAARTHEGLLVVVARDTQRAQALEAEL
KIFAGGLPVLHFPDWETLPYDVFSPHPEIVSQRIATLYRLPNVKRGVLVVPVATLMQRIA
PRSHITGSGLVLAKGQKLDLAGEQRRLEASGYRHVPQVAEPGDFAVRGALLDIFPMGTAE
PYRIELFDDEVDSIRSFDPETQRSQQQVDKVDLLPAREFPLTEEAAKEFRGNLRERFPID
VRRCPLYQDMKEGVTPGGIEYYLPLFFPQTATLFDYLADDALFVLGEGAGEAADQFWAQT
AERYDQRAHDIERPVLPPAELYLPAEKLREQLNKRLRVEVVDAGHEHAVDSGTQPAPELP
LNRKGEEPGTSLRYFLTSYPGRVLIAADSAGRREALIETLAAAGLKPQNVEGWSTFLLPL
PAGGGREGVARTGEEAKAPLPPQGIPFGHNPPLQAGEEAKYEGPKFAITIAGLEQGFALT
KPAITVLTERELYGERVRSERDRKRRRGTARDPEAIIRDLTELTPGAPIVHVDHGVGRYQ
GLVSMDVGGMDGEFLTIEYAKGDKLYVPVAQLGLVSRYSGTAPELAPLHSLGGDAWERAR
RKAAEKVRDVAAELLAIYAQRQARGGESLPIDRQLVEEFGSTFPFEETPDQESAIEAVLN
DLAAPRAMDRVICGDVGFGKTEVALRAAFATATAGRQVAVLVPTTLLAQQHYRNFADRFA
DWPVRVDVLSRFKSTKEVNEALKRLADGQIDVIVGTHKLLQPDIKFRNLGLVIVDEEQRF
GVRQKEQLKKLRAEVDLLTMTATPIPRTLNMAMAGLRDLSLIATPPAHRSAVRTFISAWD
PATIREALQRELSRGGQVYFLHNEVQSIERTVRELEGLVPDARIRVAHGQMPERELEGVM
ADFHRQRFNVLVCTTIIETGIDIPTANTIIIDRADRFGLAQLHQLRGRVGRSHHRAYAYL
VVPDRRSITADAQKRLEALASLEELGAGFTLATHDLEIRGAGELLGDEQSGQIQEIGFGL
YTELLDRAVRALKSGKVPDFDLSSEHETEVELHLPALIPDDYLPDVHARLTLYKRVASAR
SEDELRDLQVEMIDRFGLLPDSTKQLFAVASLKLMATPLGIRKLDFGANGGRIVFREKPE
VDPMTIIKLIQQLPRVYKLDGQDKLKVILDLPGASERIRSAQEVLVALGARRPA