Protein Info for OKGIIK_06680 in Rhodanobacter sp. FW510-T8

Annotation: Site-specific DNA-methyltransferase (adenine-specific)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 804 transmembrane" amino acids 342 to 366 (25 residues), see Phobius details PF12161: HsdM_N" amino acids 10 to 120 (111 residues), 42.6 bits, see alignment E=1.5e-14 TIGR00497: type I restriction-modification system, M subunit" amino acids 96 to 450 (355 residues), 246.3 bits, see alignment E=3.2e-77 PF02384: N6_Mtase" amino acids 135 to 445 (311 residues), 340.2 bits, see alignment E=1.9e-105 PF05175: MTS" amino acids 182 to 271 (90 residues), 23.1 bits, see alignment E=7.6e-09

Best Hits

KEGG orthology group: K03427, type I restriction enzyme M protein [EC: 2.1.1.72] (inferred from 75% identity to tgr:Tgr7_1779)

Predicted SEED Role

"Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72)" in subsystem Restriction-Modification System (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (804 amino acids)

>OKGIIK_06680 Site-specific DNA-methyltransferase (adenine-specific) (Rhodanobacter sp. FW510-T8)
MAIKKSELYSSLWASCDALRGGMDASQYKDYVLVLLFIKYVSDKYAGVPFAAITVPKGAS
FKDMIALKGKSDIGDQINKKIIAPLKAANKLSEMPDFNDAGKLGSGKEMVDKLTDLISIF
ENKALDFSKNRAEGDDILGDAYEYLMRHFATESGKSKGQFYTPAEVSRIMAQVLGIRDTK
TSNATTVYDPTCGSGSLLLKVADEARTKLTIYGQEKDATTAGLARMNMILHDNAEAQIVQ
GNTLTDPKFMDKGALRTFDYVVANPPFSDKRWSTGLDALNDPFERFASFGTPPAKQGDYA
YLLHIVRSLKSTGKGACILPHGVLFRGNAEAEIRRNLVRKGYIAGIIGLPANLFYGTGIP
ACIVFVDKHDAHARKGIFMIDASGGFMKDGPKNRLRSRDVHQIVDVFTRRLDIPKYSRMV
PFAEIEKNDYNLNLPRYIDSQQAEDRQDIEGHLKGGIPLADVDALQRYWEVCPDLRKTLF
KPNRPGYVDLAVDKAAIKLTIYEHPQFAAFIDGMSTHFDRWRKKSAAALKSLDAGCHPKD
VIADLSEKLLAHYAGQPLINGYDVYQHLMDYWAETMQDDLYLIAADGWKASTYRVIEQKK
NKDGKVTKEVDKGWACDLLPKSLIVTRYFVAEQAAIDQLTAEAEATEAQLTELEEEHSGE
DAVFSGFDKINKAAVKERLDEIDGDREARDEIAVLKRWQKLDREKSALKKQLKEAEVALD
AAAYAKYPQLSETEIKTLAVDDKWLGALDAAIHGEMDRISQGLTRRVRELAERYEARLPL
LVDRVAELQAKVDAHLERMGFAWR