Protein Info for OKGIIK_05850 in Rhodanobacter sp. FW510-T8

Name: infB
Annotation: translation initiation factor IF-2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 935 PF04760: IF2_N" amino acids 1 to 47 (47 residues), 26.4 bits, see alignment 1.9e-09 amino acids 361 to 407 (47 residues), 49.2 bits, see alignment 1.5e-16 PF08364: IF2_assoc" amino acids 68 to 111 (44 residues), 50.4 bits, see alignment 8.3e-17 TIGR00487: translation initiation factor IF-2" amino acids 351 to 935 (585 residues), 825.6 bits, see alignment E=2.7e-252 TIGR00231: small GTP-binding protein domain" amino acids 437 to 594 (158 residues), 106.1 bits, see alignment E=1.6e-34 PF00009: GTP_EFTU" amino acids 440 to 595 (156 residues), 125.8 bits, see alignment E=6.5e-40 PF01926: MMR_HSR1" amino acids 440 to 545 (106 residues), 38.5 bits, see alignment E=4.5e-13 PF00071: Ras" amino acids 441 to 594 (154 residues), 21.7 bits, see alignment E=5.5e-08 PF22042: EF-G_D2" amino acids 611 to 689 (79 residues), 103.8 bits, see alignment E=1.7e-33 PF11987: IF-2" amino acids 714 to 824 (111 residues), 127.1 bits, see alignment E=1.3e-40 PF03144: GTP_EFTU_D2" amino acids 856 to 923 (68 residues), 30.8 bits, see alignment 1.3e-10

Best Hits

Predicted SEED Role

"Translation initiation factor 2" in subsystem NusA-TFII Cluster or Translation initiation factors eukaryotic and archaeal or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (935 amino acids)

>OKGIIK_05850 translation initiation factor IF-2 (Rhodanobacter sp. FW510-T8)
MSDVTIKQLAQVLGMPVDRLLTQLGEAGMKFSDQEQVISSTEKVKLLGFLRRTHGKGGVA
AEVEDSAPRQITLKRRTVGELKVATPGGRGATGAAKTVNVEVRAKRTYVKRSVIAEEASV
EPEREEAVRKLQESQQQREQEERERIEAEHRRQVEAQQRALDEERQQEEKARIEVEAAGT
AEPDTTEPVAAAVETPAAEAAPASAGGEADASVQRIDQRELGMILPRIHEPRKREKLVKP
VAAPAAAAAPAVRPAAGDGTAAAAAEGGRGKSKHPRERNDIAGDKEGRESASKRFAGGQM
HLSEADRARRSSSGKRGKAARGGGRELSPRGGGSAPTGSHGFSRPTAPVVREVVVSDTNI
VAELAQKMAVKGSEVVKALFKMGVMATINQTIDHDTAVLVVEELGHTPVADNQNNAEETL
AAHTQNIELEGEKVTRPPVVTIMGHVDHGKTSLLDYIRRTKVASGEAGGITQHIGAYHVE
TSRGVITFLDTPGHAAFTSMRARGAQSTDIVVLVVAADDGVMPQTVEAVKHARAAKVPLI
VAVNKMDKDGANPDNVKQGLVQHEVVPEDWGGDVQFIPVSAKTGAGVEDLLDAISVQAEV
MELKAVADGRASGVVIESSLDRGRGPVATVLVQQGTLRKGDFVVCGVEYGRMRALIDETG
KQVAEAGPSIPVQVLGLSGVPETGDDFVAVEDERLAREVAEERQLKRRETRMVSKSNRLE
DIIAKMGQGVEQQTLNILVKGDVQGSVEALRESLTQIGNDRVRVNVVASGVGGITESDAT
LAAASKALVIGFNVRADASARKVIETNAVDVRYFSIIYDVIDQVTQAATGLLGMEVREDI
IGTAEVRDVFRSSKFGAVAGCMVTEGVVKRSKPIRVLRDHVVIFEGELESLRRFKDLVDE
VRAGMECGIAVKQYNDVKPGDQIECFERTEVARTL