Protein Info for OKGIIK_05685 in Rhodanobacter sp. FW510-T8

Annotation: 7-methyl-GTP pyrophosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 PF02545: Maf" amino acids 9 to 192 (184 residues), 174.7 bits, see alignment E=8.7e-56 TIGR00172: septum formation protein Maf" amino acids 9 to 191 (183 residues), 157 bits, see alignment E=1.9e-50

Best Hits

Swiss-Prot: 60% identical to NTPPB_BURTA: 7-methyl-GTP pyrophosphatase (BTH_I1713) from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)

KEGG orthology group: K06287, septum formation protein (inferred from 63% identity to sml:Smlt1023)

MetaCyc: 51% identical to m7GTP pyrophosphatase (Escherichia coli K-12 substr. MG1655)
RXN0-7079

Predicted SEED Role

"Septum formation protein Maf" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (198 amino acids)

>OKGIIK_05685 7-methyl-GTP pyrophosphatase (Rhodanobacter sp. FW510-T8)
MTANPPAPRIVLGSTSRYRAELLRRLLADFAQAAPGTDETPWPGEAPAARALRLAIAKAE
AVAREYRNALVIGSDQVAEIDGLVLDKPGSTERARAQLAASSGRDVHFHTALCLLDSRDG
RRCTHVDHTRVRFRELDAAEIDRYVEREQPLDCAGSFKCEGLGISLFESIDNRDPSALIG
LPLIALARMLREAGIELP