Protein Info for OKGIIK_05425 in Rhodanobacter sp. FW510-T8

Name: cobN
Annotation: cobaltochelatase subunit CobN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1327 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 1294 to 1313 (20 residues), see Phobius details PF02514: CobN-Mg_chel" amino acids 134 to 1211 (1078 residues), 985.5 bits, see alignment E=1.8e-300

Best Hits

KEGG orthology group: K02230, cobaltochelatase CobN [EC: 6.6.1.2] (inferred from 65% identity to dia:Dtpsy_2685)

Predicted SEED Role

"CobN component of cobalt chelatase involved in B12 biosynthesis" in subsystem Coenzyme B12 biosynthesis

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.6.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1327 amino acids)

>OKGIIK_05425 cobaltochelatase subunit CobN (Rhodanobacter sp. FW510-T8)
MATARSPAGIMRWMLLVALALASLFAPGPSAQATSALFVATSNVPPGKFKVLEEIARPHG
MTVEVRYLDKLPADAGPDVFDGHDIVFIDSYLQGAVRAKLGKALAQTRLPVVWVYDKAPA
AQGMPAALAQRLASYYSNGGLGNFEGFFATTVAWLGGKPATGTAAPVVVPETAIYHPDAK
QVFADTESYLRWKKVGDGARPPVIAIAFHEQYVAALQTRLIDHLIRRVEAAGAIPLAFYY
PVMGKDSMGDILAPHGRRVADAVITTRIMLSPDEPRREMEKLGIPVIQAMPYRQGDEAEW
AADPHGVSLMDVPFYMAQAEYAGIVDIQVASAMGKSDPQLQPIEAQVQTMVNKALRLVVL
QRKPVHDKRVTMFFWNYPPGEKNLSASFLNLPRSLVATLTAMQHAGYDTHTADADELTAR
LQRLLAPYYRSGRLQGLLDDDLAVRLPVADYTKWLATLPAPVRERLLRESGDPATSPMVL
GKGSQTYFVIPRLRLGKVTLMPQPPRSGAIDDREKALYHSTTAAPSHFYLAAYLWARSQS
DAFVHFGTHGTQEWLPGKERGLSVYDDPMLALGDVPVVYPYIADNIGEALQARRRGRAVI
ISHQTPPFRPAGLHDELTAIHDLLHRWLGQMDGAVRTQIMTDLLARTASAHIDLDMGWTP
ERASAEFPAFVDALHAHLHELAQTAQPLGLHTFGTAPATEHRLATVLLMLGTPFRDAAAR
HAGVRGTQLEETLAIDYDKLVQSPPYALLRQVLVEGRDPGPLDGDLAAMLKQARQWYADI
GAAGELPGLLDALAGRYVPTSYGGDPIKRPDAYPTGRNLYPFDPSRVPTQQAWEAGKKAA
EELLQAHRRDTGQLPDKLTFSLWSVETMRHEGLLEAQALWLLGVEPVWDKGGRVEGVRLV
DRKTLGRARVDVVLSITGLYRDHFPNVVKQLARAAQLAALADEADNPVAAHSKAVTAELL
GQGVDKGAATAAGQTRVFSSASGRYGTGLDDATLASDSWKGKAEGDRKLAELYLSKMQYA
YGPDPSTWGNRGVAGNDKLNLYASHLRGTDGAVLSRTSNTYGMLTTDDPFQYLGGIGLAV
RHLDGKPPKLYISNLRGGGSGKVEDAAGFLAKELSTREFHPGYIKALVAEGYAGTLSVLE
STNNLWGWTAVAREVVRDDQWEEMADVYVRDKYKLGLDAWFEKENPHAQAQIIERMLEAS
RQGYWNAKPATLETLKQRYRDLATRFDVHTDNAPFLEYVASGAPAEVAGTPAEAAAAAPS
TDAAATPAPMQQVSGMQLEKTAPADSAPSDPRAPWISAALALCLATGAARQIARRPRPYR
TSHKETP