Protein Info for OKGIIK_05125 in Rhodanobacter sp. FW510-T8

Annotation: Mechanosensitive ion channel protein MscS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 802 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 210 to 229 (20 residues), see Phobius details amino acids 250 to 272 (23 residues), see Phobius details amino acids 285 to 309 (25 residues), see Phobius details amino acids 329 to 346 (18 residues), see Phobius details amino acids 361 to 380 (20 residues), see Phobius details amino acids 401 to 431 (31 residues), see Phobius details amino acids 437 to 461 (25 residues), see Phobius details amino acids 485 to 507 (23 residues), see Phobius details amino acids 537 to 556 (20 residues), see Phobius details amino acids 577 to 599 (23 residues), see Phobius details amino acids 605 to 628 (24 residues), see Phobius details PF12607: DUF3772" amino acids 132 to 193 (62 residues), 54.6 bits, see alignment 7.4e-19 PF00924: MS_channel_2nd" amino acids 623 to 689 (67 residues), 75.9 bits, see alignment E=2.1e-25

Best Hits

KEGG orthology group: None (inferred from 45% identity to dia:Dtpsy_0786)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (802 amino acids)

>OKGIIK_05125 Mechanosensitive ion channel protein MscS (Rhodanobacter sp. FW510-T8)
MPTLLRCLLFLLLALGSTASPAQNNDQPPATAPAATPAQTLDQLGGQLDTVKAALKDNKS
GTPLADLRNSALEVQDQARQLAASLAPQMAALQAQLAVLGPVPAKGSPAEAPEVAAQRRK
LDKAQSDLDAQIKQAQLLGQGATQLAAQISGLRNDEFQARLASRTATPFSRTFWADPVRA
FPDDMVRLQRLGSRFAGAVAQAWQPPNRQPLAWCLIAAALLLGGGRWLLERLLLMLATRC
VPDGHLRRSAMAAAVALTAVLTTGLAAQLAYLGLNWNDILDEDLAALAASAVRLVCFAAY
VTGLGRALLSVQRPSWRLPALSDLAAQRLHLLPWLLAAAALLFGLLDRISRAIGTSLPAT
VTTRGLFALVISGLIGVALSRMRRSRREPAAGDAEPEQRPVWVGLLAAAAALGVAISWLG
VVTGFIALAFFVAVQMLWVGVIVATVYLLIQLLTDLINALLSPHGRGGRRLQAGFDLAPH
ALEQAAVLLAGICRVGLVLLAMATVLTPFGAGPKDLLASAEQTLGSFKLGELAIDPGSIL
GAVLVLVAGLFVLRTLKRWLREQLLPKSAMEKGMQESIVTLLGYLGGMLVFVLTLAALHV
DLKSIAWIVSALSVGIGFGLQAIVQNFISGLILLVERPVKVGDWVSLSSDVEGDIRRINV
RATEIQMWDRSTVIVPNSQLITQNVRNVTLANAQGRVQIKLPMPLDTHAGKVRGLVLGIL
GAHRDTLSAPAPYVQLESVATGAMTFNCVAYVGSPREVSGVKSELLFEILERLRSEGLPM
TSPQSMLVRTLPPLPEEDEHTG