Protein Info for OKGIIK_03675 in Rhodanobacter sp. FW510-T8

Annotation: Aminoglycoside phosphotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 PF01636: APH" amino acids 56 to 309 (254 residues), 87.1 bits, see alignment E=8.1e-29

Best Hits

KEGG orthology group: None (inferred from 60% identity to smt:Smal_0151)

Predicted SEED Role

"Putative homoserine kinase type II, PnuC-associated, THI-regulated branch" in subsystem PnuC-like transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (378 amino acids)

>OKGIIK_03675 Aminoglycoside phosphotransferase (Rhodanobacter sp. FW510-T8)
MNDPPHLAHGLAGDSTPPDWPPLALDEVAALLRGYPAPGTPLRIDWHSPRPLSAACLVAT
DRGTLFVKRHHRDVRSVATLEEEHRFIAHLRAHGMPIPAVLPDARGRTAVAIGDWTYEVH
GRAGGIDLYREAISWEPLPSRTHALTAGRMLAALHDAATGYRAPQRDTHLLVARSELIRA
ADPVAALRAQLPQRPGLADYLRGRDWPADLAELLAPWHAAAQPRLARQPSLWTHGDWHVS
NLCWSDDGADARIGAVLDFGLADANFALFDLATAIERNAIAWLALDADADAARPDIACAL
IDGYRRHRPLSSADLHLLADLLPLVHVDFALSEVEYYHAVTRSPANADIAYDTFLRGHPA
WFRLPPGQALRQAIRDHA