Protein Info for OKGIIK_03440 in Rhodanobacter sp. FW510-T8

Name: rlmKL
Annotation: bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 733 PF02926: THUMP" amino acids 38 to 158 (121 residues), 50.3 bits, see alignment E=7e-17 PF01170: UPF0020" amino acids 167 to 381 (215 residues), 163.4 bits, see alignment E=1.4e-51 PF10672: Methyltrans_SAM" amino acids 513 to 660 (148 residues), 70.2 bits, see alignment E=4.4e-23

Best Hits

Predicted SEED Role

"23S rRNA (guanine-N-2-) -methyltransferase rlmL EC 2.1.1.-)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (733 amino acids)

>OKGIIK_03440 bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL (Rhodanobacter sp. FW510-T8)
MNRLPSGAFFATCPKGMEYLLRDELVALGAGDVREALAGAHFAGTLETAYRACLWSRLAS
RILLPLAEFDAADDDALYRGVQAIDWSEHLAAHATFAVDAGTAMSKLTHSQFIGLRVKDA
VVDQFRQRDGSRPGIDTDEPDIRINVRVRRDRATLSLDLAGSPLHRRGWREEQGEAPLKE
NLAAAMLLRARWPEVYAAGGALLDPMCGSGTLLIEGALMASDVASGLRREYFGFLGWQQH
DIALWRGLLDEAKQRAETGLRALRPCFFGSDADTRMVQTAKRNAQEAGVAGFFTLDRQDV
AHAAPPPGVDYGLVITNPPYGERLGDRAEMPKLYRVLGDTLRSRFSGWRAAVLAGDVELG
RAMQLHADKRYALYNGALETVLLTFDLKPRDEKPREPKPLSAGAQMLKNRLEKNTRHLRK
RLAREGIHCWRAYDQDLPEYAAAIDVYGDTNGDDHLHIQEYRAPADIPADVARLRLREIA
RVAGEVLGVPRERIALKTRERGKGGSKYGQLDQRGEFIEVEEGGLKFLVNLTDYLDTGLF
LDHRLVRAKLRELARGRCFLNLFAYTATASAYAAAGGALETTSVDLSATYLEWASRNLAL
NGFSGARHRLMQFDALEFLQRDRGHYGLIFVDPPTFSNSKRAEDFDVQRDHVALLDACRG
RLTRDGVIVFSNNFRRFKLDREALEPHFEIEDWSAPSIPFDFARRADIHGCWLLRRRQAV
TGINPWDTAHIKK