Protein Info for OKGIIK_01680 in Rhodanobacter sp. FW510-T8

Annotation: Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 PF07221: GlcNAc_2-epim" amino acids 34 to 394 (361 residues), 396.9 bits, see alignment E=4.5e-123

Best Hits

KEGG orthology group: None (inferred from 74% identity to xcv:XCV1601)

Predicted SEED Role

"D-mannose isomerase (EC 5.3.1.7)" in subsystem Mannose Metabolism (EC 5.3.1.7)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (408 amino acids)

>OKGIIK_01680 Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family (Rhodanobacter sp. FW510-T8)
MNSAPDFRSATFLREHIAQTMAFYHPRAIDPAGGFFHYFRDDGTIYDRSHRHLVSSTRFV
FNYAMAAIEFADDAALQREYLDAARHGLRYLREVHRDPYTGGYAWTIRDERPEDRTNHAY
GAAFVLLAYASAVKAGIGEAAAWMDETWNLLERRFWDADAGLYRDEADANWQFSGYRGQN
ANMHMCEAMLAAYQASDEPRYLERALALADHMTRRQAAQAGGLVWEHYDAGWRIDWDYHR
DDPKHLFRPWGFQPGHQTEWAKLLLILEPLLLERGREENWLLPTAMHLFDTALARAWDNQ
HGGICYGFAPDGSVCDDDKYFWVQAESLAAAALLHARTGLAGYDDWYGRLWAYAWQHFVD
HRYGAWYRILTRDNRKYSDEKSPAGKTDYHTMGACHEVLALLRAGGRP