Protein Info for OKFHMN_27060 in Escherichia coli ECRC101

Name: infC
Annotation: translation initiation factor IF-3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 144 PF05198: IF3_N" amino acids 1 to 48 (48 residues), 78.7 bits, see alignment E=2.9e-26 TIGR00168: translation initiation factor IF-3" amino acids 1 to 143 (143 residues), 226.4 bits, see alignment E=8.1e-72 PF00707: IF3_C" amino acids 55 to 141 (87 residues), 124 bits, see alignment E=1.9e-40

Best Hits

Swiss-Prot: 100% identical to IF3_ECOLC: Translation initiation factor IF-3 (infC) from Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)

KEGG orthology group: K02520, translation initiation factor IF-3 (inferred from 100% identity to eco:b1718)

Predicted SEED Role

"Translation initiation factor 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (144 amino acids)

>OKFHMN_27060 translation initiation factor IF-3 (Escherichia coli ECRC101)
VSLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEI
KFRPGTDEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELA
VVESFPTKIEGRQMIMVLAPKKKQ