Protein Info for OKFHMN_23120 in Escherichia coli ECRC100

Name: yfaL
Annotation: AIDA-I family autotransporter adhesin YfaL/EhaC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1250 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details TIGR01376: chlamydial polymorphic outer membrane protein repeat" amino acids 124 to 146 (23 residues), 19.9 bits, see alignment (E = 7.4e-08) amino acids 229 to 248 (20 residues), 18 bits, see alignment (E = 3e-07) PF02415: Chlam_PMP" amino acids 127 to 145 (19 residues), 19 bits, see alignment (E = 3.2e-07) amino acids 160 to 177 (18 residues), 13 bits, see alignment (E = 2.8e-05) amino acids 228 to 245 (18 residues), 16.8 bits, see alignment (E = 1.6e-06) TIGR02601: autotransporter-associated beta strand repeat" amino acids 328 to 359 (32 residues), 31.1 bits, see alignment (E = 2.3e-11) PF12951: PATR" amino acids 328 to 357 (30 residues), 25.7 bits, see alignment (E = 2.3e-09) amino acids 556 to 580 (25 residues), 18.6 bits, see alignment (E = 3.9e-07) amino acids 663 to 691 (29 residues), 21.9 bits, see alignment (E = 3.6e-08) PF18883: AC_1" amino acids 793 to 904 (112 residues), 69.9 bits, see alignment E=4.5e-23 TIGR01414: outer membrane autotransporter barrel domain" amino acids 807 to 1250 (444 residues), 384.9 bits, see alignment E=8.5e-119 PF03212: Pertactin" amino acids 811 to 914 (104 residues), 35.3 bits, see alignment E=2.6e-12 PF03797: Autotransporter" amino acids 989 to 1228 (240 residues), 119.3 bits, see alignment E=6.3e-38

Best Hits

Swiss-Prot: 96% identical to YFAL_ECOLI: Probable autotransporter YfaL (yfaL) from Escherichia coli (strain K12)

KEGG orthology group: K07279, hypothetical protein (inferred from 98% identity to eok:G2583_2771)

Predicted SEED Role

"COG3468: Type V secretory pathway, adhesin AidA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1250 amino acids)

>OKFHMN_23120 AIDA-I family autotransporter adhesin YfaL/EhaC (Escherichia coli ECRC100)
MRVIFLRKEYLSLLPSMIASLFSANGVAAAIDLCQGYDIKASCHASRQSLSGITQVWSIA
DGQWLVFSDMTNNASGGAVFLQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKEN
STLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAIDLRVTNAVFRNNIANDGKGGAIYTINN
DIYLSDDVFNNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTAFTNNTAEGYG
GAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTF
DIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGR
SNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGSTQQTFAHSLTGFQNGTLNID
AGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDAGAVLSLEGDAAD
LAALQDDPQSIVLNGGMLDLSDFSTWQSGTSYKDGLEVSGSSGTVIGSQDVVDLAGGNDM
HIGGDGKDGVYVVIDAGDGQVSLANDNQYLGTTQIASGTLMVSDNSQLGYTHYNRQVIFT
DKPQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEG
STLTKTGAGTLELTASGTTQSAVRVEEGTLQGDVADIFPYASSLWVGDGATFVTGADQDI
QSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNCDGTLVNATDGVTLTGELNTNLET
DSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQ
LVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAY
DYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTQDPDPTPDPEPTPAYQPVLNAKVGG
YLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLF
SGRWGTDGEWMLGIVGGYSDNQGDSRSSMTGTRADNQNHGYAVGLTSSWFQHGKQKQGAW
LDNWLQYAWFSNDVSEHEDGVDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQ
DDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDASTIS
DDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW