Protein Info for OKFHMN_18625 in Escherichia coli ECRC101

Name: ygjG
Annotation: putrescine aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03372: putrescine aminotransferase
  • amino acids 45 to 486 (442 residues), 979.4 bits, E=1e-299
• PF00202: Aminotran_3
  • amino acids 111 to 485 (375 residues), 340.5 bits, E=6e-106

Best Hits

Swiss-Prot: 100% identical to PAT_ECO24: Putrescine aminotransferase (patA) from Escherichia coli O139:H28 (strain E24377A / ETEC)

KEGG orthology group: K09251, putrescine aminotransferase [EC: 2.6.1.82] (inferred from 100% identity to ecv:APECO1_3343)

MetaCyc: 100% identical to putrescine aminotransferase (Escherichia coli K-12 substr. MG1655)
Putrescine aminotransferase. [EC: 2.6.1.82]; 2.6.1.82 [EC: 2.6.1.82]; Diamine transaminase. [EC: 2.6.1.82, 2.6.1.29]

Predicted SEED Role

"Putrescine aminotransferase (EC 2.6.1.82)" in subsystem Arginine and Ornithine Degradation (EC 2.6.1.82)

MetaCyc Pathways

• superpathway of L-arginine and L-ornithine degradation (13/13 steps found)
• superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation (11/11 steps found)
• superpathway of ornithine degradation (8/8 steps found)
• L-lysine degradation I (7/7 steps found)
• L-lysine degradation X (5/6 steps found)
• putrescine degradation I (2/2 steps found)
• superpathway of L-lysine degradation (14/43 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.29 or 2.6.1.82

Protein Sequence (496 amino acids)

>OKFHMN_18625 putrescine aminotransferase (Escherichia coli ECRC101)
MITTFVFIPIFAIAAGVAQSLQYLNRYHVIREPPEHILNRLPSSASALACSAHALNLIEK
RTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQE
FIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKY
SFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPL
LPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDE
FGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLF
DNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQE
ARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIK
AARKALAAMRVSVEEA