Protein Info for OKFHMN_15880 in Escherichia coli ECRC100

Name: yiaU
Annotation: Uncharacterized HTH-type transcriptional regulator YiaU

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 PF00126: HTH_1" amino acids 9 to 66 (58 residues), 44.9 bits, see alignment E=9.3e-16 PF03466: LysR_substrate" amino acids 95 to 303 (209 residues), 55.7 bits, see alignment E=4.7e-19

Best Hits

Swiss-Prot: 99% identical to YIAU_ECOLI: Uncharacterized HTH-type transcriptional regulator YiaU (yiaU) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to eco:b3585)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (324 amino acids)

>OKFHMN_15880 Uncharacterized HTH-type transcriptional regulator YiaU (Escherichia coli ECRC100)
MTKLQLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADFESKVGLKVFDRTTRQL
MLTLFGTALLPYINDMLDRNEQLNNFIADYKHEKRGRVTIYAPTGIITYLSKHVIDKIKD
IGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDESLVASFITQYAVTAYASQRY
LEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGSKEVRDYRVKGNYVCDNTQSALE
LARNHLGIVFAPDKSVQSDLQDGTLVPCFQHPYEWWLDLVAIFRKREYQPWRVQYVLDEM
LREIRHQLAQSQQLRPEQAAESED