Protein Info for OKFHMN_10680 in Escherichia coli ECRC101

Name: mraZ
Annotation: division/cell wall cluster transcriptional repressor MraZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 152 TIGR00242: division/cell wall cluster transcriptional repressor MraZ" amino acids 1 to 152 (152 residues), 225.2 bits, see alignment E=1.4e-71 PF02381: MraZ" amino acids 1 to 75 (75 residues), 78.7 bits, see alignment E=1.3e-26 amino acids 77 to 135 (59 residues), 78 bits, see alignment E=2.1e-26

Best Hits

Swiss-Prot: 100% identical to MRAZ_ECO24: Transcriptional regulator MraZ (mraZ) from Escherichia coli O139:H28 (strain E24377A / ETEC)

KEGG orthology group: K03925, MraZ protein (inferred from 99% identity to sdy:SDY_0111)

Predicted SEED Role

"Cell division protein MraZ" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (152 amino acids)

>OKFHMN_10680 division/cell wall cluster transcriptional repressor MraZ (Escherichia coli ECRC101)
MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKL
SRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELW
DETTWHQQVKEDIDAEQLATGDLSERLQDLSL